Matijasevich Alicia, Munhoz Tiago N, Tavares Beatriz Franck, Barbosa Ana Paula Pereira Neto, da Silva Diego Mello, Abitante Morgana Sonza, Dall'Agnol Tatiane Abreu, Santos Iná S
BMC Psychiatry. 2014 Oct 8;14:284. doi: 10.1186/s12888-014-0284-x.
Standardized questionnaires designed for the identification of depression are useful for monitoring individual as well as population mental health. The Edinburgh Postnatal Depression Scale (EPDS) has originally been developed to assist primary care health professionals to detect postnatal depression, but several authors recommend its use outside of the postpartum period. In Brazil, the use of the EPDS for screening depression outside the postpartum period and among non-selected populations has not been validated. The present study aimed to assess the validity of the EPDS as a screening instrument for major depressive episode (MDE) among adults from the general population.
This is a validation study that used a population-based sampling technique to select the participants. The study was conducted in the city of Pelotas, Brazil. Households were randomly selected by two stage conglomerates with probability proportional to size. EPDS was administered to 447 adults (≥20 years). Approximately 17 days later, participants were reinterviewed by psychiatrics and psychologists using a structured diagnostic interview (Mini International Neuropsychiatric Interview, MINI). We calculated the sensitivity and specificity of each cutoff point of EPDS, and values were plotted as a receiver operator characteristic curve.
The best cutoff point for screening depression was ≥8, with 80.0% (64.4 - 90.9%) sensitivity and 87.0% (83.3 - 90.1%) specificity. Among women the best cutoff point was ≥8 too with values of sensitivity and specificity of 84.4% (67.2 - 94.7%) and 81.3% (75.5 - 86.1%), respectively. Among men, the best cutoff point was ≥7 (75% sensitivity and 89% specificity).
The EPDS was shown to be suitable for screening MDE among adults in the community.
为识别抑郁症而设计的标准化问卷对于监测个体以及人群心理健康很有用。爱丁堡产后抑郁量表（EPDS）最初是为帮助初级保健卫生专业人员检测产后抑郁症而开发的，但有几位作者建议在产后时期之外使用该量表。在巴西，EPDS在产后时期之外以及非特定人群中用于筛查抑郁症的有效性尚未得到验证。本研究旨在评估EPDS作为普通人群中成年人重度抑郁发作（MDE）筛查工具的有效性。
这是一项验证研究，采用基于人群的抽样技术选择参与者。该研究在巴西佩洛塔斯市进行。通过两阶段整群抽样，按与规模成比例的概率随机选择家庭。对447名成年人（≥20岁）进行了EPDS测试。大约17天后，由精神科医生和心理学家使用结构化诊断访谈（迷你国际神经精神访谈，MINI）对参与者进行再次访谈。我们计算了EPDS每个临界值的敏感性和特异性，并将这些值绘制成受试者工作特征曲线。
筛查抑郁症的最佳临界值为≥8，敏感性为80.0%（64.4 - 90.9%），特异性为87.0%（83.3 - 90.1%）。在女性中，最佳临界值也为≥8，敏感性和特异性分别为84.4%（67.2 - 94.7%）和81.3%（75.5 - 86.1%）。在男性中，最佳临界值为≥7（敏感性75%，特异性89%）。
EPDS被证明适用于社区中成年人MDE的筛查。
