Theede Klaus, Kiszka-Kanowitz Marianne, Nordgaard-Lassen Inge, Nielsen Anette Mertz
Gastroenheden, Medicinsk Sektion, Hvidovre Hospital, Kettegård Allé 30, 2650 Hvidovre. E-mail:
Ugeskr Laeger. 2014 Sep 8;176(37).
Faecal calprotectin is a biomarker for inflammation in the intestinal mucosa. Faecal calprotectin has the ability to detect inflammatory causes of gastrointestinal symptoms and to distinguish these from irritable bowel syndrome. The test is very sensitive but not specific to any particular gastrointestinal disease. In inflammatory bowel disease, faecal calprotectin correlates with symptoms, biochemical markers and the endoscopic findings. It can be used to monitor disease activity, treatment response and mucosal healing as well as predict relapse. We propose an algorithm for the use of faecal calprotectin in patients with unspecific abdominal complaints.
粪便钙卫蛋白是肠道黏膜炎症的生物标志物。粪便钙卫蛋白能够检测胃肠道症状的炎症原因，并将这些原因与肠易激综合征区分开来。该检测非常敏感，但并非特定于任何一种胃肠道疾病。在炎症性肠病中，粪便钙卫蛋白与症状、生化标志物及内镜检查结果相关。它可用于监测疾病活动、治疗反应和黏膜愈合情况以及预测复发。我们提出了一种在有非特异性腹部不适的患者中使用粪便钙卫蛋白的算法。
