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[炎症性肠病患者的随访:2014年消化疾病周上展示的进展]

[Follow-up of patients with inflammatory bowel disease: developments presented at Digestive Disease Week 2014].

作者信息

García-López Santiago

机构信息

Servicio de Aparato Digestivo, Hospital Universitario Miguel Servet, Zaragoza, España.

出版信息

Gastroenterol Hepatol. 2014 Sep;37 Suppl 3:31-9. doi: 10.1016/S0210-5705(14)70081-0.

Abstract

A lot of data were reported about monitoring patients with inflammatory bowel disease, with varying degrees of practical applicability. Concerning the evaluation of disease activity, it was established that objective assessments are needed. Among the techniques that we use, although endoscopy is undoubtedly the reference standard, a lot of data were presented regarding less invasive techniques. The importance of MRIs, CTs and ultrasounds (with some variations) was thus reiterated. The importance of fecal calprotectin is also reiterated, not only for colon disease, but probably small intestine disease as well. Regarding treatment monitoring, a great deal was reported about anti-TNF therapy, demonstrating again its potential role when properly used. In addition to results with infliximab, results with adalimumab were reported as very consistent. For colon cancer prevention, it seems that the clinical guidelines are achieving their objective. It also seems clear that we must improve conventional endoscopic techniques. Finally, there are other aspects that need to be considered when monitoring our patients, such as adequate sleeping patterns, anxiety or depression.

摘要

有许多关于炎症性肠病患者监测的数据报道,其实际适用性各不相同。关于疾病活动度的评估,已确定需要进行客观评估。在我们使用的技术中,虽然内镜检查无疑是参考标准,但也有许多关于侵入性较小技术的数据。因此,再次强调了磁共振成像(MRI)、计算机断层扫描(CT)和超声检查(略有差异)的重要性。粪便钙卫蛋白的重要性也再次得到强调,不仅对结肠疾病,可能对小肠疾病也同样重要。关于治疗监测,有大量关于抗TNF治疗的报道,再次证明了其合理使用时的潜在作用。除了英夫利昔单抗的结果外,阿达木单抗的结果也被报道非常一致。对于结肠癌的预防,临床指南似乎正在实现其目标。似乎也很明显,我们必须改进传统的内镜技术。最后,在监测我们的患者时,还有其他方面需要考虑,如充足的睡眠模式、焦虑或抑郁。

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