Geldof B A, van Joost T
Ned Tijdschr Geneeskd. 1989 Jul 29;133(30):1505-9.
Epoxy resin-containing products of the plastic industry are increasingly employed. We retrospectively studied the incidence and course of epoxy resin contact dermatitis in 2265 patients in whom contact dermatitis was confirmed by patch testing. A positive patch test for epoxy resin was present in 31 patients (1.4%). Exposure to epoxy resin as the cause of contact dermatitis was 'certain' in 10, 'very likely' in 9, 'possible' in 4 and 'unclear' in 8 patients. Exposure to epoxy resin was related to occupational (55%) and leisure time activities (13%). In 48% patch tests were positive for multiple test allergens. Hands (56%), arms (38%) and face (38%) were mainly affected. Re-examination of 26 of 31 patients showed that a favourable course depended on identification of the cause of the exposure to epoxy resin, avoidance of further contact and absence of sensitization to multiple allergens.
塑料工业中含环氧树脂的产品应用越来越广泛。我们回顾性研究了2265例经斑贴试验确诊为接触性皮炎患者的环氧树脂接触性皮炎的发病率及病程。31例患者(1.4%)斑贴试验对环氧树脂呈阳性。10例患者接触环氧树脂导致接触性皮炎“确定”,9例“很可能”,4例“可能”,8例“不清楚”。接触环氧树脂与职业活动(55%)和休闲活动(13%)有关。48%的患者斑贴试验对多种试验变应原呈阳性。手部(56%)、手臂(38%)和面部(38%)是主要受累部位。对31例患者中的26例进行复查发现,病情好转取决于对接触环氧树脂原因的识别、避免进一步接触以及对多种变应原无致敏。