Jolanki R, Estlander T, Kanerva L
Institute of Occupational Health, Section of Dermatology, Helsinki, Finland.
Acta Derm Venereol Suppl (Stockh). 1987;134:90-4.
Over a ten-year period (1974-1983) 542 cases of allergic occupational contact dermatitis were diagnosed in our clinic. Epoxy resins caused 71 cases (13.1%) of occupational allergic contact dermatitis (CD), and three cases (0.6%) of irritant CD. One contact urticaria was caused by an epoxy resin hardener, methyl hexahydrophthalic anhydride. Epicutaneous testing with standard epoxy resin 1% in pet. (mainly oligomer of molecular weight 340) produced allergic reactions in all the patients with allergic CD with the exception of three. These three patients had allergic reactions only to their own resins. Testing the 71 patients of allergic CD with epoxy hardeners produced allergic reactions in 19 (26.8%). None of the patients had separate delayed contact allergy to epoxy hardeners without simultaneous contact allergy to standard epoxy resin.
在十年期间（1974年至1983年），我们诊所诊断出542例过敏性职业性接触性皮炎病例。环氧树脂导致71例（13.1%）职业性过敏性接触性皮炎（CD），以及3例（0.6%）刺激性CD。1例接触性荨麻疹由环氧树脂固化剂甲基六氢邻苯二甲酸酐引起。用1%标准环氧树脂（主要为分子量340的低聚物）进行皮肤试验，除3例患者外，所有过敏性CD患者均出现过敏反应。这3例患者仅对其自身的树脂有过敏反应。用环氧树脂固化剂对71例过敏性CD患者进行检测，19例（26.8%）出现过敏反应。没有患者对环氧树脂固化剂单独出现迟发性接触过敏而不同时对标准环氧树脂有接触过敏。
