Liu Jian-Feng, Zhao Li-Rong, Lu Lai-Jin, Chen Lei, Liu Zhi-Gang, Gong Xu, Liu Bin
Department of Hand Surgery, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
The Electric Medical Branch, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Oncol Lett. 2014 Nov;8(5):1966-1972. doi: 10.3892/ol.2014.2440. Epub 2014 Aug 12.
Melanomas affect the foot and ankle region and are associated with a poor prognosis. The aim of the current study was to evaluate the functional and oncological outcomes of salvage surgery using cutaneous flaps for soft tissue reconstruction of the foot and ankle following the extended resection of a melanoma. A retrospective review was conducted to evaluate patients who presented with foot melanoma and underwent salvage surgery and defect reconstruction using three types of cutaneous flap (group S) or amputation (group A) between January 1999 and December 2010 at the First Hospital of Jilin University (Changchun, China). The postoperative mortality, surgical complications, functional outcomes and oncological outcomes were evaluated. Of the 21 patients, 11 were enrolled into group S and 10 were enrolled into group A. The median follow-up time of the patients was 58 months (range, 6-92 months). In group S, a reverse sural neurocutaneous island flap was used in six patients to perform the foot reconstruction, medial plantar flaps were used in four patients and lateral malleolus flaps were used in one patient. All 11 cutaneous flaps survived and provided satisfactory coverage. Only one cutaneous flap showed partial necrosis and required treatment comprising of debridement and regular changes to the wound dressing. The overall survival rate of patients was 65.0% and patients in the two groups experienced similar oncological outcomes. Salvage surgery with cutaneous flap reconstruction was found to be a reliable option for patients presenting with malignant melanoma of the foot and ankle.
黑色素瘤会累及足踝区域,且预后较差。本研究的目的是评估在黑色素瘤扩大切除术后,采用皮瓣进行足踝软组织重建的挽救性手术的功能和肿瘤学结局。进行了一项回顾性研究,以评估2000年1月至2010年12月期间在吉林大学第一医院(中国长春)就诊的足黑色素瘤患者,这些患者接受了挽救性手术,并使用三种皮瓣(S组)或截肢(A组)进行缺损重建。评估术后死亡率、手术并发症、功能结局和肿瘤学结局。21例患者中,11例纳入S组,10例纳入A组。患者的中位随访时间为58个月(范围6 - 92个月)。在S组中,6例患者使用腓肠神经营养血管逆行岛状皮瓣进行足部重建,4例患者使用足底内侧皮瓣,1例患者使用外踝皮瓣。所有11块皮瓣均存活,覆盖效果满意。仅1块皮瓣出现部分坏死,需进行清创及定期更换伤口敷料等处理。患者的总生存率为65.0%,两组患者的肿瘤学结局相似。对于足踝部恶性黑色素瘤患者,皮瓣重建的挽救性手术是一种可靠的选择。