Monitoring of single vesicle cytochrome-c release illuminates BAK as a novel target of Aβ oligomers.
作者信息
Linseman Daniel A
机构信息
Department of Biological Sciences and Eleanor Roosevelt Institute, University of Denver, Denver, Colorado.
出版信息
Biophys J. 2014 Oct 7;107(7):1491-2. doi: 10.1016/j.bpj.2014.08.012.
Abstract
摘要
相似文献
1
Monitoring of single vesicle cytochrome-c release illuminates BAK as a novel target of Aβ oligomers.
Biophys J. 2014 Oct 7;107(7):1491-2. doi: 10.1016/j.bpj.2014.08.012.
2
Beta-amyloid oligomers activate apoptotic BAK pore for cytochrome c release.
Biophys J. 2014 Oct 7;107(7):1601-8. doi: 10.1016/j.bpj.2014.07.074.
3
Blockade of the BAK hydrophobic groove by inhibitory phosphorylation regulates commitment to apoptosis.
PLoS One. 2012;7(11):e49601. doi: 10.1371/journal.pone.0049601. Epub 2012 Nov 26.
4
The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
J Biol Chem. 2011 Mar 18;286(11):9382-92. doi: 10.1074/jbc.M110.203638. Epub 2010 Dec 9.
5
Abeta oligomers and fibrillar aggregates induce different apoptotic pathways in LAN5 neuroblastoma cell cultures.
Biophys J. 2009 May 20;96(10):4200-11. doi: 10.1016/j.bpj.2008.11.056.
6
BH3 domains other than Bim and Bid can directly activate Bax/Bak.
J Biol Chem. 2011 Jan 7;286(1):491-501. doi: 10.1074/jbc.M110.167148. Epub 2010 Nov 1.
7
Plasminogen K5 activates mitochondrial apoptosis pathway in endothelial cells by regulating Bak and Bcl-x(L) subcellular distribution.
Apoptosis. 2011 Aug;16(8):846-55. doi: 10.1007/s10495-011-0618-9.
8
MAC inhibitors antagonize the pro-apoptotic effects of tBid and disassemble Bax / Bak oligomers.
J Bioenerg Biomembr. 2017 Feb;49(1):65-74. doi: 10.1007/s10863-015-9635-7. Epub 2015 Dec 23.
9
Bak activation for apoptosis involves oligomerization of dimers via their alpha6 helices.
Mol Cell. 2009 Nov 25;36(4):696-703. doi: 10.1016/j.molcel.2009.11.008.
10
Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release.
Mol Cell. 2008 Aug 22;31(4):570-585. doi: 10.1016/j.molcel.2008.08.002.
本文引用的文献
1
Beta-amyloid oligomers activate apoptotic BAK pore for cytochrome c release.
Biophys J. 2014 Oct 7;107(7):1601-8. doi: 10.1016/j.bpj.2014.07.074.
2
Mitochondrial membrane permeabilisation by amyloid aggregates and protection by polyphenols.
Biochim Biophys Acta. 2013 Nov;1828(11):2532-43. doi: 10.1016/j.bbamem.2013.06.026. Epub 2013 Jun 28.
3
Single-molecule imaging reveals aβ42:aβ40 ratio-dependent oligomer growth on neuronal processes.
Biophys J. 2013 Feb 19;104(4):894-903. doi: 10.1016/j.bpj.2012.12.051.
4
Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration.
J Neurosci. 2012 Oct 31;32(44):15565-76. doi: 10.1523/JNEUROSCI.3668-12.2012.
5
β-Amyloid (1-40) peptide interactions with supported phospholipid membranes: a single-molecule study.
Biophys J. 2012 Oct 3;103(7):1500-9. doi: 10.1016/j.bpj.2012.08.051. Epub 2012 Oct 2.
6
Nanoscale electrostatic domains in cholesterol-laden lipid membranes create a target for amyloid binding.
Biophys J. 2012 Aug 22;103(4):L27-9. doi: 10.1016/j.bpj.2012.06.053.
7
Two-step mechanism of membrane disruption by Aβ through membrane fragmentation and pore formation.
Biophys J. 2012 Aug 22;103(4):702-10. doi: 10.1016/j.bpj.2012.06.045.
8
Cholesterol modulates the interaction of beta-amyloid peptide with lipid bilayers.
Biophys J. 2009 May 20;96(10):4299-307. doi: 10.1016/j.bpj.2009.02.036.
9
Interaction between amyloid-beta (1-42) peptide and phospholipid bilayers: a molecular dynamics study.
Biophys J. 2009 Feb;96(3):785-97. doi: 10.1016/j.bpj.2008.09.053.
10
Apoptotic gene expression in Alzheimer's disease hippocampal tissue.
Am J Alzheimers Dis Other Demen. 2007 Aug-Sep;22(4):319-28. doi: 10.1177/1533317507302447.
Zotero 插件