Pereira L, Sampaio S, Tavares I, Bustorff M, Pestana M
Nephrology Research and Development Unit, Faculty of Medicine, University of Porto and São João Hospital Centre, Porto, Portugal.
Transpl Infect Dis. 2014 Dec;16(6):1007-11. doi: 10.1111/tid.12302. Epub 2014 Oct 9.
Campylobacter species are the leading cause of acute bacterial diarrhea in industrialized countries. However, bacteremia is detected in <1% of patients with Campylobacter enteritis and is most likely to occur in patients who are immunocompromised or of older age. To our knowledge, only 2 cases of Campylobacter jejuni bacteremia have been reported in renal transplant recipients (RTRs). We present a case of an RTR with C. jejuni bacteremia presenting as self-limiting diarrhea followed by fever and cellulitis. The patient was successfully treated with a 2-week course of imipenem and developed no other complications. We review all cases of Campylobacter bacteremia in RTRs, and discuss clinical presentation and treatment of this potentially fatal disease.
弯曲杆菌属是工业化国家急性细菌性腹泻的主要病因。然而,在弯曲杆菌肠炎患者中,菌血症的检出率不到1%,且最易发生在免疫功能低下或老年患者中。据我们所知,肾移植受者(RTRs)中仅报告过2例空肠弯曲杆菌菌血症。我们报告1例RTR发生空肠弯曲杆菌菌血症,最初表现为自限性腹泻,随后出现发热和蜂窝织炎。该患者接受了2周的亚胺培南治疗,治疗成功,未出现其他并发症。我们回顾了RTRs中所有弯曲杆菌菌血症病例,并讨论了这种潜在致命疾病的临床表现和治疗方法。