Kiralan S Sezer, Doğu-Baykut Esra, Kittipongpittaya Ketinun, McClements David Julian, Decker Eric A
Department of Food Science, University of Massachusetts Amherst , 240 Chenoweth Laboratory, 100 Holdsworth Way, Amherst, Massachusetts 01003, United States.
J Agric Food Chem. 2014 Oct 29;62(43):10561-6. doi: 10.1021/jf503115j. Epub 2014 Oct 20.
The physical location of antioxidants in oil-in-water emulsions can have significant influence on their free radical scavenging activity and ability to inhibit lipid oxidation. We aimed to determine the effect of the surfactant concentration on the partitioning behavior of tocopherols (α, γ, and δ) in oil-in-water emulsions. Tween 20 (0.1, 0.5, and 1%) increased the partitioning of the tocopherols into the aqueous phase via the formation of Tween 20-tocopherol comicelles. Partitioning behavior of antioxidants was dependent upon the number of methyl groups and, thus, polarity of the tocopherols. δ-Tocopherol (one methyl group) exhibited the most partitioning into the aqueous phase, while α-tocopherol (three methyl groups) had the lowest partitioning. Lipid oxidation studies showed that the antioxidant activity of δ- and α-tocopherols was enhanced by adding Tween 20 to oil-in-water emulsions. This work suggests that surfactant micelles could increase the antioxidant activity of tocopherols by changing their physical location.
抗氧化剂在水包油乳液中的物理位置对其自由基清除活性和抑制脂质氧化的能力可能有显著影响。我们旨在确定表面活性剂浓度对生育酚（α、γ和δ）在水包油乳液中分配行为的影响。吐温20（0.1%、0.5%和1%）通过形成吐温20 - 生育酚复合胶束增加了生育酚在水相中的分配。抗氧化剂的分配行为取决于甲基的数量，因此也取决于生育酚的极性。δ - 生育酚（一个甲基）在水相中的分配最多，而α - 生育酚（三个甲基）的分配最少。脂质氧化研究表明，向水包油乳液中添加吐温20可增强δ - 和α - 生育酚的抗氧化活性。这项工作表明，表面活性剂胶束可通过改变生育酚的物理位置来提高其抗氧化活性。
