Andrade E Silva Ulysses Vasconcellos de, Viana Luciano de Souza, Oliveira E Castro Paulo de Tarso de, Almeida Rosana Ducatti Souza, Silva Richard Sedric Pires da
Fundação Pio XII, Hospital de Câncer de Barretos, Barretos, SP, Brasil.
Rev Bras Ter Intensiva. 2011 Mar;23(1):104-7.
Intravesical instillation of bacillus Calmette-Guérin (BCG) is the treatment of choice for carcinoma in situ and non-invasive high-grade superficial tumors of the urinary bladder. This treatment is well tolerated overall, but serious complications can occur. An elderly man with coronary disease and recurrent high-grade superficial carcinoma of the bladder underwent intravesical instillation of BCG and developed septic shock. He received wide range antibiotics, tuberculostatic and vasoactive drugs, corticosteroids, mechanical ventilation and renal replacement therapy without improvement. He died nine days after the intravesical instillation of BCG because of multiple organ failure.
膀胱内灌注卡介苗（BCG）是治疗膀胱原位癌和非侵袭性高级别浅表性肿瘤的首选方法。总体而言，这种治疗耐受性良好，但可能会出现严重并发症。一名患有冠心病且复发性膀胱高级别浅表癌的老年男性接受了卡介苗膀胱内灌注，随后发生感染性休克。他接受了广泛的抗生素、抗结核药和血管活性药物治疗，还使用了皮质类固醇、机械通气和肾脏替代疗法，但病情并无改善。在卡介苗膀胱内灌注九天后，他因多器官衰竭死亡。
