大环球虫素的合成进展：天然抗癌剂
Synthetic advances in macrosphelides: natural anticancer agents.
作者信息
Paek Seung-Mann
机构信息
College of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju daero, Jinju, Gyeongnam 660-701, Korea.
出版信息
Molecules. 2014 Oct 8;19(10):15982-6000. doi: 10.3390/molecules191015982.
Abstract
Total synthesis of macrosphelides is summarized. Synthetic approaches contain the preparation of key fragments and the final ring-closure reaction for unique 16- or 15-membered macrolactone skeletons.
摘要
对大环蛇孢菌素的全合成进行了总结。合成方法包括关键片段的制备以及用于构建独特的16元或15元大环内酯骨架的最终环化反应。
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