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机器人辅助腹腔镜膀胱外输尿管再植术结局的多机构回顾

Multi-institutional review of outcomes of robot-assisted laparoscopic extravesical ureteral reimplantation.

作者信息

Grimsby Gwen M, Dwyer Moira E, Jacobs Micah A, Ost Michael C, Schneck Francis X, Cannon Glenn M, Gargollo Patricio C

机构信息

Division of Pediatric Urology, Department of Urology, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, Texas.

Department of Urology, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

出版信息

J Urol. 2015 May;193(5 Suppl):1791-5. doi: 10.1016/j.juro.2014.07.128. Epub 2014 Oct 7.

Abstract

PURPOSE

We performed a multi-institutional assessment of the outcomes and complications of robot-assisted laparoscopic extravesical ureteral reimplantation for vesicoureteral reflux in children.

MATERIALS AND METHODS

We retrospectively reviewed the records of patients who underwent robot-assisted laparoscopic extravesical ureteral reimplantation as done by 1 of 5 surgeons at Children's Medical Center, Dallas, Texas, or Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, from 2010 to 2013. Procedure failure was defined as persistent vesicoureteral reflux on postoperative voiding cystourethrogram or radionuclide cystogram and/or the need for reoperation. Multivariate logistic regression was done to identify possible risk factors for failure using STATA®, version 11.

RESULTS

A total of 61 patients (93 ureters) with a mean age of 6.7 years (range 0.6 to 18.0) underwent a procedure, of which 32 (52%) were bilateral. Ten patients (16%) underwent previous subureteral injection for vesicoureteral reflux. At a mean followup of 11.7 months the procedure was successful in 44 of 61 patients (72%). There were 14 cases of persistent vesicoureteral reflux (23%), 6 complications (10%) and 9 reoperations (11%). Multivariate logistic regression identified no factor that increased the risk of failure (p = 0.737).

CONCLUSIONS

Compared to the literature we found a notably lower success rate for robot-assisted laparoscopic extravesical ureteral reimplantation in the hands of 5 fellowship trained, robotically experienced pediatric urologists. More than 10% of patients required at least 1 reoperation for persistent vesicoureteral reflux or a surgical complication. Our experience suggests a higher complication rate and a lower success rate for robot-assisted laparoscopic ureteral reimplantation compared to the gold standard of open reimplantation.

摘要

目的

我们对机器人辅助腹腔镜下小儿膀胱输尿管反流输尿管膀胱再植术的治疗效果及并发症进行了多机构评估。

材料与方法

我们回顾性分析了2010年至2013年在得克萨斯州达拉斯儿童医疗中心或宾夕法尼亚州匹兹堡匹兹堡儿童医院,由5名外科医生之一进行机器人辅助腹腔镜下输尿管膀胱再植术的患者记录。手术失败定义为术后排尿性膀胱尿道造影或放射性核素膀胱造影显示持续存在膀胱输尿管反流和/或需要再次手术。使用STATA®11版进行多因素逻辑回归分析,以确定可能导致手术失败的危险因素。

结果

共有61例患者(93条输尿管)接受了该手术,平均年龄6.7岁(范围0.6至18.0岁),其中32例(52%)为双侧病变。10例患者(16%)曾因膀胱输尿管反流接受过输尿管下注射治疗。平均随访11.7个月,61例患者中有44例(72%)手术成功。有14例持续膀胱输尿管反流(23%)、6例并发症(10%)和9例再次手术(11%)。多因素逻辑回归分析未发现增加手术失败风险的因素(p = 0.737)。

结论

与文献报道相比,我们发现5名经过专科培训且有机器人手术经验的小儿泌尿外科医生进行的机器人辅助腹腔镜下输尿管膀胱再植术成功率明显较低。超过10%的患者因持续膀胱输尿管反流或手术并发症至少需要再次手术1次。我们的经验表明,与开放再植术这一金标准相比,机器人辅助腹腔镜输尿管再植术的并发症发生率更高,成功率更低。

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