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本文引用的文献

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Pediatric robot-assisted extravesical ureteral reimplantation (revur) in simple and complex ureter anatomy: Report of a multicenter experience.小儿机器人辅助经膀胱外输尿管再植术(revur)治疗简单和复杂输尿管解剖畸形:多中心经验报告。
J Pediatr Urol. 2023 Feb;19(1):136.e1-136.e7. doi: 10.1016/j.jpurol.2022.10.024. Epub 2022 Oct 22.
2
Extravesical vs. intravesical ureteric reimplantation for primary vesicoureteral reflux: A systematic review and meta-analysis.原发性膀胱输尿管反流的膀胱外与膀胱内输尿管再植术:一项系统评价和荟萃分析
Front Pediatr. 2022 Oct 21;10:935082. doi: 10.3389/fped.2022.935082. eCollection 2022.
3
Preoperative Bladder Bowel Dysfunction Is the Most Important Predictive Factor for Postoperative Urinary Retention After Robot-Assisted Laparoscopic Ureteral Reimplantation via An Extravesical Approach: A Multi-Center Study.术前膀胱肠道功能障碍是经腹腹腔镜输尿管再植术术后尿潴留的最重要预测因素:一项多中心研究。
J Endourol. 2021 Feb;35(2):226-233. doi: 10.1089/end.2020.0158. Epub 2021 Jan 19.
4
Postoperative bladder dysfunction and outcomes after minimally invasive extravesical ureteric reimplantation in children using a laparoscopic and a robot-assisted approach: results of a multicentre international survey.腹腔镜和机器人辅助微创经膀胱外输尿管再植术治疗儿童术后膀胱功能障碍及结局:一项多中心国际调查结果。
BJU Int. 2019 Nov;124(5):820-827. doi: 10.1111/bju.14785. Epub 2019 Sep 6.
5
Robotic-assisted laparoscopic ureteral re-implant (RALUR): Can post-operative urinary retention be predicted?机器人辅助腹腔镜输尿管再植术(RALUR):术后尿潴留能否预测?
J Pediatr Urol. 2018 Aug;14(4):323.e1-323.e5. doi: 10.1016/j.jpurol.2018.05.010. Epub 2018 Jun 7.
6
Prospective multicenter study on robot-assisted laparoscopic extravesical ureteral reimplantation (RALUR-EV): Outcomes and complications.机器人辅助腹腔镜下膀胱外输尿管再植术(RALUR-EV)的前瞻性多中心研究:结果和并发症。
J Pediatr Urol. 2018 Jun;14(3):262.e1-262.e6. doi: 10.1016/j.jpurol.2018.01.020. Epub 2018 Feb 20.
7
Robotic versus open pediatric ureteral reimplantation: Costs and complications from a nationwide sample.机器人辅助与开放式小儿输尿管再植术:来自全国样本的成本与并发症
J Pediatr Urol. 2016 Dec;12(6):408.e1-408.e6. doi: 10.1016/j.jpurol.2016.06.016. Epub 2016 Aug 23.
8
Robot-assisted Laparoscopic Extravesical Ureteral Reimplantation: Technique Modifications Contribute to Optimized Outcomes.机器人辅助腹腔镜下膀胱外输尿管再植术:技术改良有助于优化治疗效果。
Eur Urol. 2016 Nov;70(5):818-823. doi: 10.1016/j.eururo.2016.02.065. Epub 2016 Mar 30.
9
Multi-institutional review of outcomes of robot-assisted laparoscopic extravesical ureteral reimplantation.机器人辅助腹腔镜膀胱外输尿管再植术结局的多机构回顾
J Urol. 2015 May;193(5 Suppl):1791-5. doi: 10.1016/j.juro.2014.07.128. Epub 2014 Oct 7.
10
Robot-assisted extravesical ureteral reimplantation: outcomes and conclusions from 78 ureters.机器人辅助膀胱外输尿管再植术:78例输尿管的手术结果及结论
J Pediatr Urol. 2014 Oct;10(5):864-8. doi: 10.1016/j.jpurol.2014.01.028. Epub 2014 Mar 6.

用于双侧机器人输尿管再植术的卢阿·冈德蒂技术:十年来为实现最佳(解决、尿潴留和围手术期并发症)三联症结果所汲取的经验教训。

The LUAA Gundeti Technique for Bilateral Robotic Ureteral Reimplantation: Lessons Learned over a Decade for Optimal (Resolution, Urinary Retention, and Perioperative Complications) Trifecta Outcomes.

作者信息

Hajiyev Parviz, Sloan Matthew, Fialkoff Jared, Gundeti Mohan S

机构信息

Section of Urology, Department of Surgery, University of Chicago, Chicago, IL, USA.

出版信息

Eur Urol Open Sci. 2023 Sep 28;57:60-65. doi: 10.1016/j.euros.2023.09.006. eCollection 2023 Nov.

DOI:10.1016/j.euros.2023.09.006
PMID:37790798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10543781/
Abstract

BACKGROUND

Ureteral reimplantation is the gold standard treatment for high-grade vesicoureteral reflux (VUR) in pediatric patients. Robot-assisted laparoscopic extravesical ureteral reimplantation (RALUR-EV) using the LUAA technique has emerged as a viable alternative to traditional open and laparoscopic surgical correction.

OBJECTIVE

To evaluate the outcomes, reflux resolution, urinary retention, and complications associated with bilateral RALUR-EV for primary VUR using the LUAA Gundeti technique in pediatric patients.

DESIGN SETTING AND PARTICIPANTS

A retrospective study was conducted at a single academic center, involving 34 consecutive pediatric patients who underwent RALUR-EV for bilateral VUR management between December 2008 and December 2022. The study included only patients who were evaluated with postoperative voiding cystourethrogram (VCUG).

SURGICAL PROCEDURE

The LUAA extravesical ureteral reimplantation technique was performed, involving the identification and mobilization of the ureter, creation of a peritoneal window, dissection close to the neurovascular bundle, Y dissection at the ureterovesical junction, detrusorotomy, detrusorrhaphy with advential inclusion, and apical alignment suture.

MEASUREMENTS

The primary outcome was radiographic resolution of VUR on VCUG. The secondary outcomes included urinary retention and Clavien-Dindo grade III complications.

RESULTS AND LIMITATIONS

The overall radiographic resolution rate was 85.2%, with success rates of 76.7%, 75%, and 96.7% across the three distinct patient cohorts. The overall Clavien-Dindo grade III complication rate was 5.8%, and transient urinary retention was 8.8%. Resolution of urinary retention occurred within 7-28 d. The study's limitations include the small sample size, single-center design, and retrospective nature.

CONCLUSIONS

The LUAA technique demonstrates sustainable outcomes for VUR resolution with a low incidence of transient urinary retention and complications. A thorough understanding of pelvic anatomy is essential for successful dissection and minimization of the risk of complications. Further studies are needed to evaluate the effectiveness of different approaches in reducing the incidence of transient urinary retention following bilateral extravesical reimplantation.

PATIENT SUMMARY

In this study, we examined the results of the Gundeti LUAA surgical technique for treating primary vesicoureteral reflux in children. We identified various essential modifications that increase the likelihood of achieving favorable outcomes.

摘要

背景

输尿管再植术是小儿患者重度膀胱输尿管反流(VUR)的金标准治疗方法。采用LUAA技术的机器人辅助腹腔镜膀胱外输尿管再植术(RALUR-EV)已成为传统开放手术和腹腔镜手术矫正的可行替代方案。

目的

评估在小儿患者中使用LUAA Gundeti技术进行双侧RALUR-EV治疗原发性VUR的疗效、反流缓解情况、尿潴留及并发症。

设计、地点和参与者:在一个单一学术中心进行了一项回顾性研究,纳入了2008年12月至2022年12月期间连续34例因双侧VUR接受RALUR-EV治疗的小儿患者。该研究仅纳入了术后进行排尿性膀胱尿道造影(VCUG)评估的患者。

手术步骤

采用LUAA膀胱外输尿管再植技术,包括输尿管的识别与游离、腹膜窗口的创建、靠近神经血管束的解剖、输尿管膀胱交界处的Y形解剖、逼尿肌切开、带外膜包埋的逼尿肌缝合以及顶端对齐缝合。

测量指标

主要结局是VCUG上VUR的影像学缓解情况。次要结局包括尿潴留和Clavien-DindoⅢ级并发症。

结果与局限性

总体影像学缓解率为85.2%,三个不同患者队列的成功率分别为76.7%、75%和96.7%。总体Clavien-DindoⅢ级并发症发生率为5.8%,短暂性尿潴留发生率为8.8%。尿潴留于7 - 28天内缓解。该研究的局限性包括样本量小、单中心设计以及回顾性研究性质。

结论

LUAA技术在VUR缓解方面显示出可持续的疗效,短暂性尿潴留和并发症发生率低。全面了解盆腔解剖结构对于成功解剖和将并发症风险降至最低至关重要。需要进一步研究评估不同方法在降低双侧膀胱外再植术后短暂性尿潴留发生率方面的有效性。

患者总结

在本研究中,我们检查了Gundeti LUAA手术技术治疗小儿原发性膀胱输尿管反流的结果。我们确定了各种有助于提高获得良好结局可能性的重要改进措施。