Nasr Joanna, Ammoury Alfred, Chouairy Camil, Mégarbané Halal, El Habr Constantin
J Med Liban. 2014 Jul-Sep;62(3):176-9. doi: 10.12816/0006220.
Linear IgA bullous dermatosis (LAD) is an autoimmune subepidermal blistering disorder. LAD may be either idiopathic or drug related; the most common drug being vancomycin. The clinical presentations of both idiopathic and drug-related LAD are variable and may mimic other blistering disorders. We report a case of a 76-year-old man known to have a renal cell carcinoma who presented a vancomycin-induced LAD that clinically mimicked toxic epidermal necrolysis (TEN).
线状IgA大疱性皮病(LAD)是一种自身免疫性表皮下大疱性疾病。LAD可能是特发性的,也可能与药物相关;最常见的相关药物是万古霉素。特发性和药物相关LAD的临床表现各不相同,可能会模仿其他大疱性疾病。我们报告一例76岁男性病例,该患者患有肾细胞癌,出现了万古霉素诱导的LAD,临床上酷似中毒性表皮坏死松解症(TEN)。