Mushi E, Kinshuck A, Svecova N, Schache A, Jones T M, Tandon S, Lancaster J
Otolaryngology and Head and Neck Department, Aintree University Hospital, Liverpool, UK.
Clin Otolaryngol. 2015 Apr;40(2):93-7. doi: 10.1111/coa.12322.
To determine the feasibility of drain-free surgery in selective neck dissection (SND) by investigating the effects of the use of synthetic fibrin glue Tisseel™ on the drain output and overall wound healing.
Retrospective case review.
Tertiary referral unit in Head and Neck surgery.
The case notes of 30 patients who had undergone SND in levels I to IV were examined and compared. Tisseel was applied prior to wound closure in fifteen patients only.
Drain output, number of days of drain in situ and total number of days of hospitalisation as well as complications rate and type between the Tisseel and non-Tisseel groups.
Patients who had Tisseel applied in the wound had a mean drain output of 67.1 ml, which was significantly lower than 174.4 ml in patients who did not have it. Patients in the Tisseel group had the drain in situ for a shorter period and were hospitalised for fewer days than the ones in the non-Tisseel group.
The use of Tisseel in SND resulted in lower drain output and shorter period of drain in situ and hospitalisation. There was no additional morbidity or complication associated with its use, and the initial conclusion is that this technique may have benefits not only to patient recovery but also for healthcare providers as they could potentially reduce the overall costs of surgery by reducing the length of hospital stay.
通过研究使用合成纤维蛋白胶Tisseel™对引流液量及伤口整体愈合的影响，确定在选择性颈清扫术（SND）中不放置引流管手术的可行性。
回顾性病例分析。
头颈外科三级转诊单位。
检查并比较了30例行Ⅰ至Ⅳ区SND患者的病历。仅15例患者在伤口闭合前使用了Tisseel。
Tisseel组与非Tisseel组之间的引流液量、引流管留置天数、总住院天数以及并发症发生率和类型。
伤口使用Tisseel的患者平均引流液量为67.1毫升，显著低于未使用Tisseel的患者的174.4毫升。Tisseel组患者的引流管留置时间较短，住院天数也少于非Tisseel组患者。
在SND中使用Tisseel可减少引流液量、缩短引流管留置时间和住院时间。使用该产品未出现额外的发病率或并发症，初步结论是该技术不仅可能有益于患者康复，还可能对医疗服务提供者有益，因为它有可能通过缩短住院时间来降低手术的总体成本。
