Hughes Mary J, Stein Paul D, Matta Fadi
Department of Osteopathic Medical Specialties, Michigan State University College of Osteopathic Medicine, East Lansing, Michigan, United States.
Department of Osteopathic Medical Specialties, Michigan State University College of Osteopathic Medicine, East Lansing, Michigan, United States.
Thromb Res. 2014 Dec;134(6):1182-5. doi: 10.1016/j.thromres.2014.09.036. Epub 2014 Oct 2.
The purpose of this investigation was to determine the prevalence of silent pulmonary embolism (PE) in patients with deep venous thrombosis (DVT) limited to the calf veins.
This is a systematic review. We attempted to identify all published investigations that reported the prevalence of silent PE in patients with infrapopliteal DVT. Studies were identified by searching PubMed through January 2014. The search was augmented by manually reviewing the references in all original articles and in reviews.
The prevalence of silent PE in patients with DVT limited to the calf veins was described in 6 investigations. Pooled data showed a prevalence of 24 of 183 (13.1%) (95% CI 8.9-18.8%).
Silent PE in patients with DVT limited to the calf veins is not rare. Imaging at the time of diagnosis of calf vein DVT, typically with a perfusion scan alone, may be useful, but there is an economic cost and exposure to radiation.
本研究旨在确定仅累及小腿静脉的深静脉血栓形成（DVT）患者中无症状肺栓塞（PE）的患病率。
这是一项系统评价。我们试图找出所有已发表的报告腘下DVT患者无症状PE患病率的研究。通过检索截至2014年1月的PubMed来识别研究。通过人工查阅所有原始文章和综述中的参考文献来扩大检索范围。
6项研究描述了仅累及小腿静脉的DVT患者中无症状PE的患病率。汇总数据显示，183例中有24例（13.1%）（95%可信区间8.9 - 18.8%）。
仅累及小腿静脉的DVT患者中的无症状PE并不罕见。在诊断小腿静脉DVT时进行影像学检查，通常仅进行灌注扫描，可能是有用的，但存在经济成本和辐射暴露问题。
