Tolou C, Mahieu L, Salmon L, Hamid S, Suarez C, Garcia D, Pagot-Mathis V, Gomane C, Berot A, Malecaze F, Soler V
Centre de la rétine, hôpital Paule-de-Viguier, CHU de Toulouse, 330, avenue de Grande-Bretagne TSA 70034, 31059 Toulouse cedex 9, France; Laboratoire GR2DE, Inserm UMRS1043, centre de physiopathologie de Toulouse Purpan, place Baylac, 31059 Toulouse, France.
Centre de la rétine, hôpital Paule-de-Viguier, CHU de Toulouse, 330, avenue de Grande-Bretagne TSA 70034, 31059 Toulouse cedex 9, France.
J Fr Ophtalmol. 2014 Dec;37(10):796-803. doi: 10.1016/j.jfo.2014.04.013. Epub 2014 Oct 11.
Acute macular neuroretinopathy is a retinal disease, usually presenting with a "normal fundus". Thus, this condition can be mistaken for optic neuropathy. Herein we present five clinical cases of patients affected with acute macular neuroretinopathy; one of them is a retrospective diagnosis while the others were diagnosed on initial examination. In the five cases, multimodal imaging with infrared photography and OCT helped to establish the diagnosis.
Retrospective study of five clinical cases. Initial and final best visual acuities as well as infrared and OCT imaging were collected for all patients.
All patients initially reported a visual disturbance associated with a more or less severe decrease in visual acuity. Infrared imaging showed a dark, perifoveolar appearance of the lesions. In all cases, OCT images showed thickening and hyperreflectivity of the outer plexiform layer, extending towards the outer retinal layers.
Acute macular neuroretinopathy is a clinical entity that has been long-described, which now benefits widely from new imaging technologies, allowing an earlier and more accurate diagnosis, but calling into question the actual name of this condition. The exact pathophysiology of the condition remains nonetheless incompletely elucidated.
急性黄斑神经视网膜病变是一种视网膜疾病,通常表现为“眼底正常”。因此,这种情况可能会被误诊为视神经病变。在此,我们介绍五例急性黄斑神经视网膜病变患者的临床病例;其中一例为回顾性诊断,其他几例在初诊时即被确诊。在这五例病例中,红外摄影和光学相干断层扫描(OCT)的多模态成像有助于确诊。
对五例临床病例进行回顾性研究。收集了所有患者的初始和最终最佳视力以及红外和OCT成像资料。
所有患者最初均报告有视力障碍,视力或多或少有严重下降。红外成像显示病变呈暗的、黄斑中心凹周围外观。在所有病例中,OCT图像显示外丛状层增厚且反射增强,延伸至视网膜外层。
急性黄斑神经视网膜病变是一种早已被描述的临床实体,现在广泛受益于新的成像技术,能够更早、更准确地诊断,但该疾病的实际名称也受到质疑。然而,该疾病的确切病理生理学仍未完全阐明。