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儿童毛母质瘤

Pilomatrixoma in childhood.

作者信息

Kose Dogan, Ciftci Ilhan, Harmankaya Ismail, Ugras Serdar, Caliskan Umran, Koksal Yavuz

机构信息

Department of Pediatric Hematology and Oncology, Necmettin Erbakan University, Konya, Turkey.

出版信息

J Cancer Res Ther. 2014 Jul-Sep;10(3):549-51. doi: 10.4103/0973-1482.137918.

Abstract

CONTEXT

Pilomatrixoma is a benign tumor of the skin. Malignant transformation can be seen rarely in the small percentage.

AIM

The aim of the following study is to attract attention to this tumor in the differential diagnosis because if it is not kept in mind it leads to both unnecessary interventions and treatments for the patient.

PATIENTS AND METHODS

From January 2006 to December 2012, 8 patients with pilomatrixoma were evaluated retrospectively.

RESULTS

A total of 8 pediatric pilomatrixoma patients' charts were reviewed retrospectively. None of the patients had familial feature. Of 8 patients 4 (50%) were male and 4 (50%) were female. The patients' age ranged from 2-18 years with a median age 11.5 years. All of the patients were admitted with the complaint of swelling at the lesion site. Two patients have multiple lesions, one of them has two and other has three lesions. A total of 11 lesion were detected in our 8 patients that 5 of them were located upper extremities (46%), 3 of them cervical region (27%), 2 of them on occipital region (18%) and 1 of them in the sacral region (9%). All lesions were excised completely. Until now, no patient had evidence of recurrence or malignant disease.

CONCLUSION

As a result pilomatrixoma is a benign tumor, with atypical forms and unfortunately, no tumor-specific diagnostic feature except of a careful histopathological examination is available.

摘要

背景

毛发上皮瘤是一种皮肤良性肿瘤。在极少数情况下可发生恶性转化。

目的

以下研究的目的是在鉴别诊断中引起对这种肿瘤的关注,因为如果不考虑它,会给患者带来不必要的干预和治疗。

患者与方法

回顾性评估2006年1月至2012年12月期间的8例毛发上皮瘤患者。

结果

回顾性分析了8例儿童毛发上皮瘤患者的病历。所有患者均无家族特征。8例患者中,4例(50%)为男性,4例(50%)为女性。患者年龄在2至18岁之间,中位年龄为11.5岁。所有患者均因病变部位肿胀而入院。2例患者有多个病灶,其中1例有2个病灶,另1例有3个病灶。8例患者共检测到11个病灶,其中5个位于上肢(46%),3个位于颈部(27%),2个位于枕部(18%),1个位于骶部(9%)。所有病灶均被完全切除。到目前为止,没有患者出现复发或恶性疾病的迹象。

结论

毛发上皮瘤是一种良性肿瘤,具有非典型形式,不幸的是,除了仔细的组织病理学检查外,没有肿瘤特异性诊断特征。

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