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成人声门下狭窄的环状气管切除术与分期喉气管成形术的对比研究。

A comparative study of cricotracheal resection and staged laryngotracheoplasty for adult subglottic stenosis.

作者信息

Ching Harry H, Mendelsohn Abie H, Liu Isabelle Y, Long Jennifer, Chhetri Dinesh K, Berke Gerald S

机构信息

Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA

出版信息

Ann Otol Rhinol Laryngol. 2015 Apr;124(4):326-33. doi: 10.1177/0003489414554942. Epub 2014 Oct 14.

Abstract

OBJECTIVE

Cricotracheal resection (CTR) and laryngotracheoplasty (LTP) are open surgical treatments for severe subglottic stenosis. This study aims to compare the applications and outcomes of these techniques.

METHOD

Patients with subglottic stenosis at a tertiary academic institution from 2000 to 2012 were identified by diagnosis codes. Patients who underwent LTP or CTR were included. Records were reviewed for treatment data and outcomes. Patients with a history of head and neck malignancy or stenosis without cricoid involvement were excluded.

RESULT

Sixty-one and 20 patients underwent LTP and CTR, respectively. When comparing patients receiving LTP and CTR, there was a significant difference in stenosis etiology (P=.014). The groups were similar in Cotton-Myer grade (P=.102). At last follow-up, 80.3% of LTP patients and 90.0% of CTR patients were decannulated. On multivariate analysis, there was a significant association between stenosis grade and decannulation in the LTP group (P=.01). Decannulation was not associated with stenosis grade in the CTR group. In both groups, there was no significant association between decannulation and sex, stenosis etiology, or stenosis length.

CONCLUSION

Cricotracheal resection and LTP have both shown excellent long-term decannulation rates. Etiology and stenosis grade are likely to be determining factors when recommending specific surgical interventions for subglottic stenosis.

摘要

目的

环状气管切除术(CTR)和喉气管成形术(LTP)是治疗严重声门下狭窄的开放性手术。本研究旨在比较这些技术的应用及结果。

方法

通过诊断编码确定2000年至2012年在一家三级学术机构中患有声门下狭窄的患者。纳入接受LTP或CTR的患者。回顾记录以获取治疗数据和结果。排除有头颈部恶性肿瘤病史或环状软骨未受累的狭窄患者。

结果

分别有61例和20例患者接受了LTP和CTR。比较接受LTP和CTR的患者时,狭窄病因存在显著差异(P = 0.014)。两组在科顿-迈尔分级方面相似(P = 0.102)。在最后一次随访时,80.3%的LTP患者和90.0%的CTR患者拔管。多因素分析显示,LTP组狭窄分级与拔管之间存在显著关联(P = 0.01)。CTR组拔管与狭窄分级无关。在两组中,拔管与性别、狭窄病因或狭窄长度之间均无显著关联。

结论

环状气管切除术和LTP均显示出优异的长期拔管率。在为声门下狭窄推荐特定手术干预措施时,病因和狭窄分级可能是决定因素。

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