Le Loc T, Partridge John Colin, Tran Bich H, Le Vui T, Duong Tuan K, Nguyen Ha T, Newman Thomas B
Department of Pediatrics, University of California, San Francisco, Box 0748, 533 Parnassus Ave, U585, San Francisco, CA 94143, USA.
BMC Pediatr. 2014 Oct 14;14:264. doi: 10.1186/1471-2431-14-264.
The National Hospital of Pediatrics in Vietnam performed >200 exchange transfusions annually (2006-08), often on infants presenting encephalopathic from lower-level hospitals. As factors delaying care-seeking are not known, we sought to study care practices and traditional beliefs relating to neonatal jaundice in northern Vietnam.
We conducted a prospective, cross-sectional, population-based, descriptive study from November 2008 through February 2010. We prospectively identified mothers of newborns through an on-going regional cohort study. Trained research assistants administered a 78-item questionnaire to mothers during home visits 14-28 days after birth except those we could not contact or whose babies remained hospitalized at 28 days.
We enrolled 979 mothers; 99% delivered at a health facility. Infants were discharged at a median age of 1.35 days. Only 11% received jaundice education; only 27% thought jaundice could be harmful. During the first week, 77% of newborns were kept in dark rooms. Only 2.5% had routine follow-up before 14 days. Among 118 mothers who were worried by their infant's jaundice but did not seek care, 40% held non-medical beliefs about its cause or used traditional therapies instead of seeking care. Phototherapy was uncommon: 6 (0.6%) were treated before discharge and 3 (0.3%) on readmission. However, there were no exchange transfusions, kernicterus cases, or deaths.
Early discharge without follow-up, low maternal knowledge, cultural practices, and use of traditional treatments may limit or delay detection or care-seeking for jaundice. However, in spite of the high prevalence of these practices and the low frequency of treatment, no bad outcomes were seen in this study of nearly 1,000 newborns.
越南国家儿科医院每年进行超过200例换血治疗(2006 - 2008年),对象多为从基层医院转诊来的患有脑病的婴儿。由于延误就医的因素尚不清楚,我们试图研究越南北方与新生儿黄疸相关的就医行为和传统观念。
我们于2008年11月至2010年2月进行了一项前瞻性、横断面、基于人群的描述性研究。通过一项正在进行的区域队列研究前瞻性地确定新生儿的母亲。经过培训的研究助理在婴儿出生14 - 28天后进行家访时,向母亲发放一份包含78个条目的问卷,但无法联系到的母亲或其婴儿在28天时仍住院的情况除外。
我们纳入了979名母亲;99%在医疗机构分娩。婴儿出院的中位年龄为1.35天。只有11%接受了黄疸教育;只有27%认为黄疸可能有害。在第一周,77%的新生儿被安置在黑暗的房间里。只有2.5%在14天前进行了常规随访。在118名因婴儿黄疸而担忧但未就医的母亲中,40%对黄疸病因持有非医学观念,或使用传统疗法而非就医。光疗并不常见:6例(0.6%)在出院前接受了治疗,3例(0.3%)在再次入院时接受了治疗。然而,没有进行换血治疗,也没有发生核黄疸病例或死亡。
早期出院且无随访、母亲知识水平低、文化习俗以及传统治疗方法的使用可能会限制或延迟黄疸的发现或就医行为。然而,尽管这些情况普遍存在且治疗频率较低,但在这项近1000名新生儿的研究中未观察到不良后果。