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从药物到设计药物的发展

[The development from drug to designer drug].

作者信息

Askaa Bjarke, Horwitz Henrik, Wøien Vidar André, Høgberg Lotte C G, Jürgens Gesche

机构信息

Klinisk Farmakologisk Afdeling, Bispebjerg -Hospital, Bispebjerg Bakke 23, 2400 København NV.

出版信息

Ugeskr Laeger. 2014 Oct 13;176(42).

Abstract

Synthetic "designer drugs" with hallucinogenic properties have become increasingly popular among recreational drug users in recent years. Some of the designer drugs are chemically modified drugs previously used in treatment of depression and chronic fatigue. The drugs are available from a large number of internet distributers. There is very little knowledge of the clinical symptoms and how intoxicated people should be treated. We present a review of published literature (including 284 intoxicated patients) and experiences from the Danish poison centre concerning two chemical derivatives of earlier registered drugs.

摘要

近年来,具有致幻特性的合成“设计药物”在娱乐性吸毒者中越来越受欢迎。一些设计药物是以前用于治疗抑郁症和慢性疲劳的化学改性药物。这些药物可从大量互联网经销商处购得。对于其临床症状以及中毒者应如何治疗,人们了解甚少。我们对已发表的文献(包括284名中毒患者)以及丹麦毒物中心关于两种早期注册药物的化学衍生物的经验进行了综述。

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