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美国放射学会适宜性标准(®)非脊柱骨转移瘤

ACR Appropriateness Criteria(®) non-spine bone metastases.

作者信息

Kim Edward Y, Chapman Tobias R, Ryu Samuel, Chang Eric L, Galanopoulos Nicholas, Jones Joshua, Kubicky Charlotte D, Lee Charles P, Teh Bin S, Traughber Bryan J, Van Poznak Catherine, Vassil Andrew D, Weber Kristy, Lo Simon Shek-Man

机构信息

1 University of Washington , Seattle, Washington.

出版信息

J Palliat Med. 2015 Jan;18(1):11-7. doi: 10.1089/jpm.2014.9395.

Abstract

Bone metastases are a common clinical problem, affecting many types of cancer patients. The presence of tumor in bone can cause significant morbidity including pain, neurological dysfunction, hypercalcemia, and pathological fracture leading to functional loss. The optimal treatment of a patient with bone metastases depends on many factors, including evaluation of the patient's goals of care, performance status, mechanical stability of the affected bone, life expectancy, and overall extent of disease. Treatment options may include radiotherapy, systemic therapies, surgical stabilization, medical pain management, and radiopharmaceuticals. Ideal management of bone metastases requires a coordinated multidisciplinary approach among diagnostic radiologists, radiation oncologists, medical oncologists, orthopedic surgeons, pain specialists, physiatrists, and palliative care specialists. The American College of Radiology Appropriateness Criteria(®) are evidence-based guidelines for specific clinical conditions that are reviewed every 3 years by a multidisciplinary expert panel. The guidelines development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances where evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment.

摘要

骨转移是一个常见的临床问题,影响着许多类型的癌症患者。骨骼中肿瘤的存在会导致严重的发病率,包括疼痛、神经功能障碍、高钙血症以及导致功能丧失的病理性骨折。骨转移患者的最佳治疗取决于许多因素,包括对患者护理目标、身体状况、受累骨骼的机械稳定性、预期寿命以及疾病总体范围的评估。治疗选择可能包括放射治疗、全身治疗、手术固定、药物止痛管理以及放射性药物。骨转移的理想管理需要诊断放射科医生、放射肿瘤学家、医学肿瘤学家、骨科医生、疼痛专家、物理治疗师和姑息治疗专家之间进行协调的多学科方法。美国放射学会适宜性标准(®)是针对特定临床情况的循证指南,由多学科专家小组每3年进行一次审查。指南的制定和审查包括对同行评审期刊上的当前医学文献进行广泛分析,并应用成熟的共识方法(改良德尔菲法)由专家小组对成像和治疗程序的适宜性进行评分。在缺乏证据或证据不明确的情况下,可能会采用专家意见来推荐成像或治疗。

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