Chen Na, Xie Juan
PPSM, ENS Cachan, CNRS UMR 8531, 61 av President Wilson, F-94230 Cachan, France.
J Org Chem. 2014 Nov 7;79(21):10716-21. doi: 10.1021/jo502128h. Epub 2014 Oct 28.
N-Oxyamide-containing compounds have shown improved metabolic stability and interesting secondary structures due to the good hydrogen bond-donating property of N-oxyamide. β-Glucolipids linked by the N-oxyamide bond have been successfully synthesized as novel mimics of glycoglycerolipids and glycosphingolipids.
含N-氧酰胺的化合物由于N-氧酰胺具有良好的氢键供体性质，已显示出改善的代谢稳定性和有趣的二级结构。通过N-氧酰胺键连接的β-葡萄糖脂已成功合成，作为糖甘油脂和糖鞘脂的新型模拟物。
