Gunji Naohiko, Katakura Kyoko, Takahashi Atsushi, Fujiwara Tatsuo, Suzuki Ryoma, Watanabe Hiroshi, Ohira Hiromasa
Department of Gastroenterology and Rheumatology, Fukushima Medical University, Japan.
Intern Med. 2014;53(20):2319-24. doi: 10.2169/internalmedicine.53.2765. Epub 2014 Oct 15.
A 39-year-old man presented with diarrhea and abdominal pain. At 26 years of age, he was found to have eosinophilia and abnormal liver function parameters, for which prednisolone therapy was started. He subsequently underwent a liver biopsy and endoscopic retrograde cholangiopancreatography, and received a diagnosis of primary sclerosing cholangitis (PSC). On presentation to our hospital, he was further diagnosed with eosinophilic colitis based on aggravation of diarrhea and severe eosinophilic infiltration in the colonic mucosa. We herein report a rare case of concurrent PSC and eosinophilic colitis.
一名39岁男性因腹泻和腹痛就诊。26岁时，他被发现患有嗜酸性粒细胞增多症和肝功能参数异常，为此开始使用泼尼松龙治疗。随后他接受了肝活检和内镜逆行胰胆管造影，并被诊断为原发性硬化性胆管炎（PSC）。在我院就诊时，基于腹泻加重和结肠黏膜严重嗜酸性粒细胞浸润，他被进一步诊断为嗜酸性粒细胞性结肠炎。我们在此报告一例罕见的PSC与嗜酸性粒细胞性结肠炎并存的病例。
