Wang Hai-Jun, Ye You-Fan, Shen Yin, Zhu Rui, Yao Dong-Xiao, Zhao Hong-Yang
Department of Neurosurgery, Huazhong University of Science and Technology, Wuhan, 430022, China.
Department of Ophthalmology, Huazhong University of Science and Technology, Wuhan, 430022, China.
J Huazhong Univ Sci Technolog Med Sci. 2014 Oct;34(5):716-721. doi: 10.1007/s11596-014-1341-x. Epub 2014 Oct 16.
The clinical characteristics of patients who presented in poor clinical grade due to ruptured middle cerebral artery aneurysms (MCAAs) associated with large sylvian hematomas (SylH) were analyzed and an ingenious designed prophylactic hinged craniectomy was introduced. Twenty-eight patients were graded into Hunt-Hess grades IV-V and emergency standard micro-neurosurgeries (aneurysm clipping, hematoma evacuation and prophylactic hinged craniectomy) were performed, and their clinical data were retrospectively analyzed. 46.43% of the patients reached encouraged favorable outcomes on discharge. The favorable outcome group and the poor outcome group significantly differed in terms of patients' anisocoria, Hunt-Hess grade before surgery, extent of the midline shift and time to the surgery after bleeding (P<0.05). There were no significant differences in age, sex, volume and location of the hematoma, size of aneurysm between the favorable and poor groups (P>0.05). However, ingenious designed prophylactic hinged craniectomy efficiently reduced the patients' intracranial pressure (ICP) after surgery. It was suggested that preoperative conditions such as Hunt-Hess grading, extent of the midline shift and the occurrence of cerebral hernia affect the prognosis of patients, but time to the surgery after bleeding and prophylactic hinged craniectomy are of significant importance for optimizing the prognosis of MCAA patients presenting with large SylH.
分析了因大脑中动脉动脉瘤(MCAAs)破裂伴大脑外侧裂大血肿(SylH)而临床分级较差的患者的临床特征,并介绍了一种精心设计的预防性带蒂颅骨切除术。28例患者被分级为Hunt-Hess IV - V级,并进行了急诊标准显微神经外科手术(动脉瘤夹闭、血肿清除和预防性带蒂颅骨切除术),对其临床资料进行回顾性分析。46.43%的患者出院时达到了令人鼓舞的良好预后。良好预后组和不良预后组在患者瞳孔不等大、术前Hunt-Hess分级、中线移位程度和出血后至手术的时间方面存在显著差异(P<0.05)。良好组和不良组在年龄、性别、血肿体积和位置、动脉瘤大小方面无显著差异(P>0.05)。然而,精心设计的预防性带蒂颅骨切除术有效降低了患者术后的颅内压(ICP)。提示术前如Hunt-Hess分级、中线移位程度和脑疝的发生等情况影响患者预后,但出血后至手术的时间和预防性带蒂颅骨切除术对优化伴有大脑外侧裂大血肿的MCAAs患者的预后具有重要意义。