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高钙血症:前列腺腺癌的一项指示性发现

[Hypercalcemia: a finding indicative of a prostatic adenocarcinoma].

作者信息

Llarena Ibarguren R, Acha Pérez M, Zabala Egurrola J A, Pertusa Peña C

出版信息

Actas Urol Esp. 1989 Sep-Oct;13(5):409-10.

PMID:2531967
Abstract

Calcemic alterations in prostate cancer are extremely rare. Hypercalcemia may be seen in cases of multiple osseous dissemination, and even in the absence of this in response to humoral mechanisms. The existence of hypercalcemia may indicate tumoural recurrence, and may at times be a datum prior to the diagnosis of the tumour. In cases of disseminated prostate adenocarcinoma hormones treatment may secure the normalization of blood calcium. We present a case of prostate carcinoma diagnosed in a 76-year-old patient, as a result of the presentation of a hypercalcemic metabolic syndrome, which was corrected after treatment by means of complete androgenic blocking.

摘要

前列腺癌中的血钙改变极为罕见。高钙血症可见于多处骨转移的病例,甚至在无骨转移时因体液机制也可出现。高钙血症的存在可能提示肿瘤复发,有时可能是肿瘤诊断前的一个数据。在转移性前列腺腺癌病例中,激素治疗可使血钙恢复正常。我们报告一例76岁患者,因出现高钙血症代谢综合征而诊断为前列腺癌,经完全雄激素阻断治疗后得以纠正。

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