肛门直肠畸形与唐氏综合征。

Anorectal malformations and Down syndrome.

作者信息

Zlotogora J, Abu-Dalu K, Lernau O, Sagi M, Voss R, Cohen T

机构信息

Department of Human Genetics, Hadassah Hospital Ein Karem, Hebrew University Hadassah Medical School, Jerusalem, Israel.

出版信息

Am J Med Genet. 1989 Nov;34(3):330-1. doi: 10.1002/ajmg.1320340307.

DOI:10.1002/ajmg.1320340307

PMID:2531980

Abstract

During 1980 to 1986, 89 children with Down syndrome and 42 with imperforate anus were diagnosed among 64,870 liveborn infants in the Jewish population of Jerusalem. Two of the children had both Down syndrome and imperforate anus. This indicates a high incidence of imperforate anus among children with Down syndrome (2.2%).

摘要

1980年至1986年期间，在耶路撒冷的犹太人口中，64870名活产婴儿中有89名被诊断患有唐氏综合征，42名患有肛门闭锁。其中两名儿童同时患有唐氏综合征和肛门闭锁。这表明唐氏综合征患儿中肛门闭锁的发病率很高（2.2%）。