马达加斯加塔那那利佛的医生目前对抗链球菌溶血素O（ASO）水平进行评估的做法。
Current practice about the evaluation of antibody to streptolysin O (ASO) levels by physicians working in Antananarivo, Madagascar.
作者信息
Zafindraibe Norosoa Julie, Randriamanantany Zely Arivelo, Rajaonatahina Davidra Hendriso, Andriamahenina Ramamonjisoa, Rasamindrakotroka Andry
机构信息
University center hospital of Antananarivo, Para clinic unit of immunology, Antananarivo, Madagascar.
University center Hospital of Fianarantsoa, Laboratory unit, fianarantsoa, Madagascar.
出版信息
Afr Health Sci. 2014 Jun;14(2):384-9. doi: 10.4314/ahs.v14i2.14.
INTRODUCTION
The diagnosis of post streptococcal diseases is usually confirmed by immunological tests. Only the antistreptolysin O is usually prescribed by physician. This study aimed to describe the current practice of these requests in Antananarivo.
METHODS
It was a retrospective and descriptive study conducted at the Para clinic Unit of Immunology at the University Center Hospital of Antananarivo. We analyzed all requests during seven years, from January 2003 to December 2009. We looked at age, gender, and clinical symptoms which led to the request and the result for each request.
RESULTS
We retained 4143 requests for antistreptolysin O titration in our study. The mean age of the study participants was 32.9 years with 18.3% of participants being less than 15 years old. The main symptoms leading to the request of this analysis were rheumatologic (41%), followed by neurological (13.9%) and cardiologic symptoms (8.5%) and 19.4% were prescribed for various symptoms. Only 15% of all requests had a value more than 200 U/ml.
CONCLUSION
Our study found that in most of requests, ASO titre levels were not significant.
引言
链球菌感染后疾病的诊断通常通过免疫学检测来确诊。医生通常仅开具抗链球菌溶血素O检测。本研究旨在描述塔那那利佛目前这些检测申请的情况。
方法
这是一项在塔那那利佛大学中心医院免疫学门诊进行的回顾性描述性研究。我们分析了2003年1月至2009年12月七年间的所有检测申请。我们研究了提出申请的患者的年龄、性别、导致申请的临床症状以及每项申请的结果。
结果
我们的研究纳入了4143份抗链球菌溶血素O滴度检测申请。研究参与者的平均年龄为32.9岁，18.3%的参与者年龄小于15岁。导致此项分析申请的主要症状为风湿性症状（41%），其次是神经学症状（13.9%）和心脏病学症状（8.5%），19.4%的申请是因各种症状而开具。所有申请中只有15%的值超过200 U/ml。
结论
我们的研究发现，在大多数申请中，抗链球菌溶血素O滴度水平并不显著。
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