• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

胃切除术用于治疗经90Y微球放射性栓塞后难治性胃溃疡。

Gastrectomy for the treatment of refractory gastric ulceration after radioembolization with 90Y microspheres.

作者信息

Yim Sun Young, Kim Jin Dong, Jung Jin Yong, Kim Chang Ha, Seo Yeon Seok, Yim Hyung Joon, Um Soon Ho, Ryu Ho Sang, Kim Yun Hwan, Kim Chong Suk, Shin Eun

机构信息

Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.

Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. ; Department of Internal Medicine, Cheju Halla General Hospital, Jeju, Korea.

出版信息

Clin Mol Hepatol. 2014 Sep;20(3):300-5. doi: 10.3350/cmh.2014.20.3.300. Epub 2014 Sep 25.

DOI:10.3350/cmh.2014.20.3.300
PMID:25320734
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4197179/
Abstract

Transcatheter arterial radioembolization (TARE) with Yttrium-90 ((90)Y)-labeled microspheres has an emerging role in treatment of patients with unresectable hepatocellular carcinoma. Although complication of TARE can be minimized by aggressive pre-evaluation angiography and preventive coiling of aberrant vessels, radioembolization-induced gastroduodenal ulcer can be irreversible and can be life-threatening. Treatment of radioembolization-induced gastric ulcer is challenging because there is a few reported cases and no consensus for management. We report a case of severe gastric ulceration with bleeding that eventually required surgery due to aberrant deposition of microspheres after TARE.

摘要

钇-90（90Y）标记微球的经导管动脉放射性栓塞术（TARE）在不可切除肝细胞癌患者的治疗中发挥着越来越重要的作用。尽管通过积极的术前评估血管造影和对异常血管进行预防性栓塞可将TARE的并发症降至最低，但放射性栓塞引起的胃十二指肠溃疡可能是不可逆的，甚至可能危及生命。由于放射性栓塞引起的胃溃疡报道病例较少且治疗尚无共识，因此其治疗具有挑战性。我们报告一例TARE后因微球异常沉积导致严重胃溃疡伴出血，最终需要手术治疗的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa6e/4197179/21f80ccb4708/cmh-20-300-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa6e/4197179/8babaca83c7e/cmh-20-300-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa6e/4197179/4268a84957a9/cmh-20-300-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa6e/4197179/0d30f8096411/cmh-20-300-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa6e/4197179/21f80ccb4708/cmh-20-300-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa6e/4197179/8babaca83c7e/cmh-20-300-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa6e/4197179/4268a84957a9/cmh-20-300-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa6e/4197179/0d30f8096411/cmh-20-300-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa6e/4197179/21f80ccb4708/cmh-20-300-g004.jpg

相似文献

1
Gastrectomy for the treatment of refractory gastric ulceration after radioembolization with 90Y microspheres.胃切除术用于治疗经90Y微球放射性栓塞后难治性胃溃疡。
Clin Mol Hepatol. 2014 Sep;20(3):300-5. doi: 10.3350/cmh.2014.20.3.300. Epub 2014 Sep 25.
2
Gastric injury from (90)Y to left hepatic lobe tumors adjacent to the stomach: fact or fiction?胃附近左肝叶肿瘤接受（90）钇治疗导致的胃损伤：事实还是虚构？
Eur J Nucl Med Mol Imaging. 2015 Dec;42(13):2038-44. doi: 10.1007/s00259-015-3122-6. Epub 2015 Jul 21.
3
Radioembolization with infusion of yttrium-90 microspheres into a right inferior phrenic artery with hepatic tumor supply is feasible and safe.经肝肿瘤供血的右下肋间动脉输注钇-90 微球进行放射性栓塞是可行且安全的。
J Vasc Interv Radiol. 2012 Oct;23(10):1294-301. doi: 10.1016/j.jvir.2012.07.009. Epub 2012 Aug 24.
4
Yttrium-90 microsphere induced gastrointestinal tract ulceration.钇-90微球诱导的胃肠道溃疡形成。
World J Surg Oncol. 2008 Sep 2;6:93. doi: 10.1186/1477-7819-6-93.
5
Microvascular injury in persistent gastric ulcers after yttrium-90 microsphere radioembolization for liver malignancies.钇-90微球放射性栓塞治疗肝脏恶性肿瘤后持续性胃溃疡中的微血管损伤
Hum Pathol. 2016 Apr;50:11-4. doi: 10.1016/j.humpath.2015.10.016. Epub 2015 Nov 11.
6
Radioembolization with use of yttrium-90 resin microspheres in patients with hepatocellular carcinoma and portal vein thrombosis.钇[90Y]树脂微球放射性栓塞治疗肝细胞癌合并门静脉血栓形成患者。
J Vasc Interv Radiol. 2010 Aug;21(8):1205-12. doi: 10.1016/j.jvir.2010.04.012. Epub 2010 Jul 3.
7
Histological changes in nontumoral liver secondary to radioembolization of hepatocellular carcinoma with yttrium 90-impregnated microspheres: report of two cases.肝细胞癌经钇90微球放射性栓塞后非肿瘤性肝脏的组织学变化：2例报告
Semin Liver Dis. 2014 Nov;34(4):465-8. doi: 10.1055/s-0034-1394145. Epub 2014 Nov 4.
8
Survival benefit of radioembolization for inoperable hepatocellular carcinoma using yttrium-90 microspheres.使用钇-90微球进行放射性栓塞对不可切除肝细胞癌的生存获益。
J Gastroenterol Hepatol. 2014 Nov;29(11):1897-904. doi: 10.1111/jgh.12621.
9
Resin Versus Glass Microspheres for Y Transarterial Radioembolization: Comparing Survival in Unresectable Hepatocellular Carcinoma Using Pretreatment Partition Model Dosimetry.树脂微球与玻璃微球用于 Y 型经动脉放射性栓塞治疗：使用预处理分区模型剂量学比较不可切除肝细胞癌的生存情况。
J Nucl Med. 2017 Aug;58(8):1334-1340. doi: 10.2967/jnumed.116.184713. Epub 2017 Jan 12.
10
Same-Day Yttrium-90 Radioembolization: Feasibility with Resin Microspheres.同日钇-90放射性栓塞术：使用树脂微球的可行性
J Vasc Interv Radiol. 2019 Mar;30(3):314-319. doi: 10.1016/j.jvir.2018.10.016.

引用本文的文献

1
Transcatheter Arterial Radioembolization-Induced Gastric Ulcer in an Excluded Stomach After Roux-en-Y Gastric Bypass.经导管动脉放射性栓塞术致 Roux-en-Y 胃旁路术后排除胃内的胃溃疡
ACG Case Rep J. 2024 Jun 26;11(7):e01399. doi: 10.14309/crj.0000000000001399. eCollection 2024 Jul.
2
Extrahepatic Y Complication; Gastric Ulcer Secondary to Y Therapy for Liver Metastasis Despite Negative Preprocedural Imaging.肝外Y并发症；尽管术前影像学检查为阴性，但肝转移瘤Y治疗后继发胃溃疡
Nucl Med Mol Imaging. 2024 Apr;58(2):86-91. doi: 10.1007/s13139-023-00828-z. Epub 2023 Nov 10.
3
Radioembolization for hepatocellular carcinoma: what clinicians need to know.

本文引用的文献

1
Hepatic radioembolization complicated by gastrointestinal ulceration.肝动脉放射性栓塞并发胃肠道溃疡
Semin Intervent Radiol. 2011 Jun;28(2):240-5. doi: 10.1055/s-0031-1280673.
2
Radioembolization results in longer time-to-progression and reduced toxicity compared with chemoembolization in patients with hepatocellular carcinoma.与化疗栓塞相比，放射性栓塞可使肝癌患者的疾病进展时间延长且毒性降低。
Gastroenterology. 2011 Feb;140(2):497-507.e2. doi: 10.1053/j.gastro.2010.10.049. Epub 2010 Oct 30.
3
Current role of selective internal irradiation with yttrium-90 microspheres in the management of hepatocellular carcinoma: a systematic review.
肝细胞癌的放射性栓塞治疗：临床医生需要了解的内容。
J Liver Cancer. 2022 Mar;22(1):4-13. doi: 10.17998/jlc.2022.01.16. Epub 2022 Feb 23.
4
Therapeutic approach of adipose-derived mesenchymal stem cells in refractory peptic ulcer.脂肪间充质干细胞治疗难治性消化性溃疡的方法。
Stem Cell Res Ther. 2021 Sep 26;12(1):515. doi: 10.1186/s13287-021-02584-3.
5
Long-Term Palliative Effect of Stenting in Gastric Outlet Obstruction Due to Transarterial Chemoembolization with Yttrium-90 in a Patient with Metastatic Neuroendocrine Tumor.钇-90经动脉化疗栓塞治疗转移性神经内分泌肿瘤致胃出口梗阻患者中支架置入的长期姑息效果
Clin Endosc. 2016 Sep;49(5):479-482. doi: 10.5946/ce.2015.149. Epub 2016 Jun 29.
6
Diagnostic and Treatment Approaches for Refractory Peptic Ulcers.难治性消化性溃疡的诊断与治疗方法
Clin Endosc. 2015 Jul;48(4):285-90. doi: 10.5946/ce.2015.48.4.285. Epub 2015 Jul 24.
钇-90 微球选择性内放疗在肝细胞癌治疗中的作用：系统评价。
Int J Radiat Oncol Biol Phys. 2011 Oct 1;81(2):460-7. doi: 10.1016/j.ijrobp.2010.06.010. Epub 2010 Oct 1.
4
Nonoperative therapies for combined modality treatment of hepatocellular cancer: expert consensus statement.肝癌联合治疗的非手术治疗方法：专家共识声明。
HPB (Oxford). 2010 Jun;12(5):313-20. doi: 10.1111/j.1477-2574.2010.00183.x.
5
Gastroduodenal ulceration associated with radioembolization for the treatment of hepatic tumors: an institutional experience and review of the literature.放射性栓塞治疗肝肿瘤相关的胃十二指肠溃疡：机构经验和文献复习。
Dig Dis Sci. 2010 Sep;55(9):2450-8. doi: 10.1007/s10620-010-1156-y. Epub 2010 Mar 3.
6
Complications following radioembolization with yttrium-90 microspheres: a comprehensive literature review.钇-90微球放射性栓塞术后并发症：一项全面的文献综述
J Vasc Interv Radiol. 2009 Sep;20(9):1121-30; quiz 1131. doi: 10.1016/j.jvir.2009.05.030. Epub 2009 Jul 29.
7
Radiation microsphere-induced GI ulcers after selective internal radiation therapy for hepatic tumors: an underrecognized clinical entity.肝肿瘤选择性内放射治疗后放射性微球诱导的胃肠道溃疡：一种未被充分认识的临床实体。
Gastrointest Endosc. 2009 Sep;70(3):561-7. doi: 10.1016/j.gie.2009.03.015. Epub 2009 Jul 4.
8
Gastroduodenitis associated with yttrium 90-microsphere selective internal radiation: an iatrogenic complication in need of recognition.与钇90微球选择性内照射相关的胃十二指肠炎症：一种需要识别的医源性并发症。
Arch Pathol Lab Med. 2008 Nov;132(11):1734-8. doi: 10.5858/132.11.1734.
9
Safety and efficacy of 90Y radiotherapy for hepatocellular carcinoma with and without portal vein thrombosis.90Y放疗对伴有和不伴有门静脉血栓形成的肝细胞癌的安全性和疗效
Hepatology. 2008 Jan;47(1):71-81. doi: 10.1002/hep.21980.
10
Radioembolization with 90Y microspheres: angiographic and technical considerations.90Y微球放射性栓塞：血管造影及技术考量
Cardiovasc Intervent Radiol. 2007 Jul-Aug;30(4):571-92. doi: 10.1007/s00270-007-9064-z. Epub 2007 May 22.