Li Lan, Zhao Yu, Ma Xiangyu, Zhang Delun, Wu Zebin, Chen Shan
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2014 Aug;28(15):1145-8.
To explore the clinical manifestations in pediatric laryngopharyngeal reflux and to provide more information on diagnosis and treatment.
Sixty-two cases with recurrent respiratory infections, hoarseness and chronic cough were examined with reflux symptom index (RSI), reflux finding score (RFS), and 24-hour pH monitoring. Those who had at least two positive test for reflux were given PPI for diagnostic therapy.
All patients completed reflux symptom index (RSI) questionnaire and underwent fiberoptic laryngoscopy, and reflux finding score (RFS) was evaluated. The positive rate of RSI and RFS was 91.94% and 79.03% differently. 24-hours pH monitoring and diagnostic therapy was about 30.76% and 85.48% differently. The symptoms show hoarseness 90.32%, postnasal drip 77.42%, difficulty swallowing 74.19%, abdominal pain and chest pain 72.58%, throat clearing 64.52%, chronic cough 56.45%, dysphagia 51.61%, throat abnormal feeling 48.39%. Laryngoscope examination shows inter-arytenoid erythema 100%, vocal mucosal oedema 75.81%, diffuse laryngeal edema 50.00%, posterior commissure hypertrophy 33.87%, subglottic edema 4.84%, no granuloma case. There was 16 cases showing positive in 24-hours pH monitoring test. The positive rate was 30.76%. All cases accepted diagnostic therapy. Fifty-three cases were effective. The positive rate was 85.48%.
There are no clinical presentations specific to pediatric laryngopharyngeal reflux. Patients often present with a wide range of atypical symptoms and signs. RSI questionnaire and RFS may provide diagnostic datas. Primary treatment includes lifestyle and medical therapy.
探讨小儿喉咽反流的临床表现,为诊断和治疗提供更多信息。
对62例反复呼吸道感染、声音嘶哑及慢性咳嗽患儿进行反流症状指数(RSI)、反流发现评分(RFS)及24小时pH监测。反流检查至少两项阳性者给予质子泵抑制剂进行诊断性治疗。
所有患者均完成反流症状指数(RSI)问卷调查并接受纤维喉镜检查,同时评估反流发现评分(RFS)。RSI和RFS的阳性率分别为91.94%和79.03%。24小时pH监测及诊断性治疗的阳性率分别约为30.76%和85.48%。症状表现为声音嘶哑90.32%、鼻后滴漏77.42%、吞咽困难74.19%、腹痛和胸痛72.58%、清嗓64.52%、慢性咳嗽56.45%、咽下困难51.61%、咽喉部异物感48.39%。喉镜检查显示杓间区红斑100%、声带黏膜水肿75.81%、弥漫性喉水肿50.00%、后联合肥大33.87%、声门下水肿4.84%,无肉芽肿病例。24小时pH监测试验阳性16例,阳性率为30.76%。所有病例均接受诊断性治疗,53例有效,有效率为85.48%。
小儿喉咽反流无特异性临床表现,常表现为多种非典型症状和体征。RSI问卷调查及RFS可提供诊断依据。主要治疗方法包括生活方式调整及药物治疗。