Abe Hayato, Mafune Ken-Ichi, Minamimura Keisuke, Hirata Tooru
Division of Gastrointestinal Surgery, Mitsui Memorial Hospital, Tokyo, Japan.
Dig Surg. 2014;31(4-5):269-75. doi: 10.1159/000365293. Epub 2014 Oct 14.
This study assessed the validity of the Estimation of Physiologic Ability and Surgical Stress (E-PASS) score in maintenance hemodialysis patients undergoing elective abdominal surgery.
We retrospectively reviewed the medical records of 73 hemodialysis patients who underwent elective gastrointestinal surgery. The main outcomes analyzed were the E-PASS score and postoperative course, which were defined by mortality and morbidity. The discriminative capability of the E-PASS score was evaluated using receiver operating characteristic (ROC) curve analysis.
The overall mortality rate observed was 2.7% (2 patients) and the morbidity rate was 36.9%. There were no significant differences in the comprehensive risk score, preoperative score or surgical stress score for patients with or without complications (p = 0.556, 0.639 and 0.168, respectively). Subsequent ROC curve analysis demonstrated poor predictive accuracy for morbidity. When the results in our study population were compared with those in Haga's study population, our population exhibited a highly significant rightward shift (p < 0.001).
The E-PASS score was a poor predictor of complications because maintenance hemodialysis patients already have relatively high risk factors. This scoring system should not be applied in such a special group with high risk factors.
本研究评估了生理能力与手术应激评估(E-PASS)评分在接受择期腹部手术的维持性血液透析患者中的有效性。
我们回顾性分析了73例接受择期胃肠手术的血液透析患者的病历。分析的主要结局为E-PASS评分和术后病程,术后病程由死亡率和发病率定义。采用受试者工作特征(ROC)曲线分析评估E-PASS评分的鉴别能力。
观察到的总死亡率为2.7%(2例患者),发病率为36.9%。有并发症和无并发症患者的综合风险评分、术前评分或手术应激评分无显著差异(分别为p = 0.556、0.639和0.168)。随后的ROC曲线分析显示发病率的预测准确性较差。当将我们研究人群的结果与Haga研究人群的结果进行比较时,我们的人群呈现出高度显著的右移(p < 0.001)。
由于维持性血液透析患者已经存在相对较高的危险因素,E-PASS评分对并发症的预测能力较差。该评分系统不应应用于这类具有高危险因素的特殊人群。