Chapoutot L, Metz D, Jolly D, Laudinat J M, Pollet E, Taupin J M, Elaerts J, Bajolet A
Service de Cardiologie, Hôpital Robert-Debré, Reims.
Ann Cardiol Angeiol (Paris). 1989 Nov;38(9):523-9.
In 41 patients with acute or recent pulmonary embolus (PE), a prospective study was conducted with cardiac Doppler sonography (CDS). The test is performed first in all patients, then immediately following a treatment fibrinolytics in 10 of them. The PE is confirmed by pulmonary angiography in 39 patients and embolectomy for the 2 patients who presented a mobile thrombus in the right atrium. A tricuspid insufficiency (TI) is almost always recorded by continuous Doppler: the systolic pulmonary artery pressure (sPAP) is calculated from the maximum velocity of the regurgitating tricuspid flow, using Bernouilli's equation. The correlation between Doppler sPAP and sPAP obtained by catheterization is: r = 0.95 (n = 34; p less than 0.001). A severe pulmonary hypertension, corresponding to a TI exceeding 3.5 m/s is related to a pulmonary migration occurring on a pathological heart. There is a satisfactory relationship between the elevation of the Doppler sPAP and the degree of pulmonary obstruction in the "Pe on healthy heart" population: r = 0.6 (n = 29; p less than 0.001). The dilated right ventricle observed on the sonogram (RV) is proportional to the severity of the angiographic image: correlation between the RV/LV ratio and the percentage of vascular obstruction is r = 0.73 (n = 27; p less than 0.001). The drop in the sPAP and the regression of the symptoms of pulmonary heart noted on CDS after fibrinolysis, correspond to a significant improvement of the pulmonary perfusion. The CDS seems to be absolutely necessary in PE because of the major and reliable informations it provides.
对41例急性或近期发生肺栓塞(PE)的患者进行了心脏多普勒超声检查(CDS)的前瞻性研究。首先对所有患者进行该检查,然后对其中10例患者在溶栓治疗后立即进行检查。39例患者通过肺血管造影确诊为PE,另外2例右心房有活动血栓的患者接受了栓子切除术。连续多普勒几乎总能记录到三尖瓣反流(TI):利用伯努利方程,根据三尖瓣反流的最大速度计算收缩期肺动脉压(sPAP)。多普勒sPAP与导管插入术测得的sPAP之间的相关性为:r = 0.95(n = 34;p < 0.001)。TI超过3.5 m/s对应的严重肺动脉高压与病理性心脏上发生的肺转移有关。在“健康心脏合并PE”人群中,多普勒sPAP升高与肺阻塞程度之间存在良好的相关性:r = 0.6(n = 29;p < 0.001)。超声心动图上观察到的右心室扩张(RV)与血管造影图像的严重程度成正比:RV/LV比值与血管阻塞百分比之间的相关性为r = 0.73(n = 27;p < 0.001)。溶栓后CDS显示sPAP下降以及肺心病症状消退,这对应着肺灌注的显著改善。由于CDS能提供重要且可靠的信息,所以它在PE诊断中似乎是绝对必要的。