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硬皮病患者的胃肠道症状及其对体重指数和生活质量的影响。

Gastrointestinal symptoms in scleroderma patients and its influence in body mass index and quality of life.

作者信息

Skare T, Culpi M, Yokoo P, Dias M

出版信息

Acta Reumatol Port. 2014 Jul-Sep;39(3):242-7.

Abstract

BACKGROUND

Scleroderma (SSc) gastrointestinal (GI) symptoms may affect nutritional status and patients' quality of life.

OBJECTIVE

To study prevalence of GI symptoms and its relationship to nutritional profile and quality of life of patients with SSc.

METHODS

Fifty two SSc patients and 51 controls were studied for BMI (body mass index), dietary recall, major GI symptoms and quality of life by SF-12 questionnaire.

RESULTS

BMI in scleroderma patients was lower than controls (p=0.02) despite an almost similar food intake. Scleroderma patients had higher prevalence of upper gastrointestinal tract symptoms than controls (heartburn, nausea and vomiting, dysphagia and epigastric pain) that were not associated with BMI (p= 0.36) but diminished quality of life (p=0.02).

CONCLUSIONS

SSc patients have a lower BMI than controls and higher prevalence of GI symptoms that does not affect food intake but diminishes quality of life.

摘要

背景

硬皮病(SSc)的胃肠道(GI)症状可能会影响营养状况和患者的生活质量。

目的

研究SSc患者胃肠道症状的患病率及其与营养状况和生活质量的关系。

方法

通过SF - 12问卷对52例SSc患者和51例对照者进行体重指数(BMI)、饮食回顾、主要胃肠道症状及生活质量的研究。

结果

尽管硬皮病患者的食物摄入量与对照者几乎相似,但其BMI低于对照者(p = 0.02)。硬皮病患者上消化道症状(烧心、恶心和呕吐、吞咽困难及上腹部疼痛)的患病率高于对照者,这些症状与BMI无关(p = 0.36),但会降低生活质量(p = 0.02)。

结论

SSc患者的BMI低于对照者,胃肠道症状的患病率更高,这些症状不影响食物摄入,但会降低生活质量。

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