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运动起始和结束反应的等效电路模型。

An equivalent circuit model for onset and offset exercise response.

作者信息

Zhang Yi, Haddad Azzam, Su Steven W, Celler Branko G, Coutts Aaron J, Duffield Rob, Donges Cheyne E, Nguyen Hung T

机构信息

The Faculty of Aeronautics and Astronautics, University of Electronic Science and Technology of China, 611731 Chengdu, China.

出版信息

Biomed Eng Online. 2014 Oct 18;13:145. doi: 10.1186/1475-925X-13-145.

Abstract

BACKGROUND

The switching exercise (e.g., Interval Training) has been a commonly used exercise protocol nowadays for the enhancement of exerciser's cardiovascular fitness. The current difficulty for simulating human onset and offset exercise responses regarding the switching exercise is to ensure the continuity of the outputs during onset-offset switching, as well as to accommodate the exercise intensities at both onset and offset of exercise.

METHODS

Twenty-one untrained healthy subjects performed treadmill trials following both single switching exercise (e.g., single-cycle square wave protocol) and repetitive switching exercise (e.g., interval training protocol). During exercise, heart rate (HR) and oxygen uptake (VO2) were monitored and recorded by a portable gas analyzer (K4b 2, Cosmed). An equivalent single-supply switching resistance-capacitor (RC) circuit model was proposed to accommodate the observed variations of the onset and offset dynamics. The single-cycle square wave protocol was utilized to investigate the respective dynamics at onset and offset of exercise with the aerobic zone of approximate 70%-77% of HR max, and verify the adaption feature for the accommodation of different exercise strengths. The design of the interval training protocol was to verify the transient properties during onset-offset switching. A verification method including Root-mean-square-error (RMSE) and correlation coefficient, was introduced for comparisons between the measured data and model outputs.

RESULTS

The experimental results from single-cycle square wave exercises clearly confirm that the onset and offset characteristics for both HR and VO2 are distinctly different. Based on the experimental data for both single and repetitive square wave exercise protocols, the proposed model was then presented to simulate the onset and offset exercise responses, which were well correlated indicating good agreement with observations.

CONCLUSIONS

Compared with existing works, this model can accommodate the different exercise strengths at both onset and offset of exercise, while also depicting human onset and offset exercise responses, and guarantee the continuity of outputs during onset-offset switching. A unique adaption feature by allowing the time constant and steady state gain to re-shift back to their original states, more closely mimics the different exercise strengths during normal daily exercise activities.

摘要

背景

转换运动(如间歇训练)是目前常用的一种运动方案,用于提高运动者的心血管适能。当前在模拟人类关于转换运动的起始和结束运动反应时的难点在于,要确保在起始-结束转换过程中输出的连续性,同时要适应运动起始和结束时的运动强度。

方法

21名未经训练的健康受试者按照单次转换运动(如单周期方波方案)和重复转换运动(如间歇训练方案)进行了跑步机试验。在运动过程中,通过便携式气体分析仪(K4b 2,Cosmed)监测并记录心率(HR)和摄氧量(VO2)。提出了一个等效单电源开关电阻-电容(RC)电路模型,以适应观察到的起始和结束动态变化。利用单周期方波方案研究了运动起始和结束时在大约70%-77%最大心率的有氧区域的各自动态,并验证了适应不同运动强度的特性。间歇训练方案的设计是为了验证起始-结束转换过程中的瞬态特性。引入了一种包括均方根误差(RMSE)和相关系数的验证方法,用于比较测量数据和模型输出。

结果

单周期方波运动的实验结果清楚地证实,HR和VO2的起始和结束特征明显不同。基于单次和重复方波运动方案的实验数据,提出了该模型来模拟起始和结束运动反应,两者相关性良好,表明与观察结果吻合度高。

结论

与现有研究相比,该模型能够适应运动起始和结束时的不同运动强度,同时描绘人类的起始和结束运动反应,并保证起始-结束转换过程中输出的连续性。通过允许时间常数和稳态增益重新回到其原始状态的独特适应特性,更紧密地模拟了日常正常运动活动中的不同运动强度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a19/4219124/789fe7759fbd/12938_2014_879_Fig1_HTML.jpg

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