Kaur Sukhjot, Mahajan Rajesh, Jain Narender Pal, Sood Neena, Chhabra Sandeep
J Assoc Physicians India. 2014 Jan;62(1):54-7.
Kikuchi's disease is a rare, benign, self-limited disorder, characterised clinically by fever and tender regional lymphadenopathy. It has been reported worldwide and is particularly common in people of Asian descent. The cause of Kikuchi's disease is unknown. It predominantly affects young females and can closely mimic several infectious and immunological conditions. Histopathologic features of lymph nodes in Kikuchi's disease are characteristic and permit differentiation of this benign condition from lymphomas, systemic lupus erythematosus and infectious lymphadenopathies. We report a female patient presenting with fever and tender cervical lymphadenopathy. She was being treated for tubercular lymphadenitis and was referred after she developed a transient hepatitis and a skin rash following treatment with anti-tubercular drugs. An excisional biopsy of the lymph node revealed histiocytic necrotising lymphadenitis, consistent with Kikuchi's disease. A brief review of the pathogenesis and differential diagnosis of Kikuchi's disease is presented.
菊池病是一种罕见的、良性的、自限性疾病，临床特征为发热和局部淋巴结压痛。该病在全球均有报道，在亚裔人群中尤为常见。菊池病的病因尚不清楚。它主要影响年轻女性，并且可能与多种感染性和免疫性疾病极为相似。菊池病患者淋巴结的组织病理学特征具有特异性，可将这种良性疾病与淋巴瘤、系统性红斑狼疮及感染性淋巴结病区分开来。我们报告了一名出现发热和颈部淋巴结压痛的女性患者。她正在接受结核性淋巴结炎的治疗，在使用抗结核药物治疗后出现了短暂性肝炎和皮疹，随后前来就诊。淋巴结切除活检显示为组织细胞坏死性淋巴结炎，符合菊池病。本文对菊池病的发病机制和鉴别诊断进行了简要综述。
