一种用于靶向癌症治疗的单体光敏剂。
A monomeric photosensitizer for targeted cancer therapy.
机构信息
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China.
出版信息
Chem Commun (Camb). 2014 Dec 11;50(95):14983-6. doi: 10.1039/c4cc07628a.
PMID:25327438
Abstract
A targeted photosensitizer used in photodynamic therapy (PDT) was fabricated by incorporation of zinc phthalocyanine (ZnPc) and folic acid (FA) into polyvinylpyrrolidone (PVP) micelles, which exhibits excellent anticancer performance revealed by both in vitro studies and in vivo tests.
摘要
通过将锌酞菁（ZnPc）和叶酸（FA）掺入聚维酮（PVP）胶束中，制备了一种用于光动力疗法（PDT）的靶向光敏剂，体外研究和体内试验均表明其具有优异的抗癌性能。
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