1型糖尿病患儿及青少年的瞳孔大小

Pupillary size in children and adolescents with type 1 diabetes.

作者信息

Clarke C F, Piesowicz A T, Spathis G S

机构信息

Queen Mary's Hospital for Children, Carshalton, UK.

出版信息

Diabet Med. 1989 Dec;6(9):780-3. doi: 10.1111/j.1464-5491.1989.tb01278.x.

DOI:10.1111/j.1464-5491.1989.tb01278.x

PMID:2533036

Abstract

Pupillary adaptation to darkness was studied in 63 children and adolescents with Type 1 diabetes using a simple portable pupillometer. Results were compared with those in a group of age-related non-diabetic children and expressed as the ratio of the pupil diameter to the iris diameter (pupil diameter %). In the diabetic patients the pupil diameter % was 61.1 +/- 5.8 (44.4-71.9) % compared with 64.2 +/- 4.1 (53.2-72.6) % in the control subjects (p less than 0.001). Abnormal pupillary adaptation to darkness was found more commonly than abnormal heart rate variation in response to a variety of stimuli in the diabetic patients. Pupillary adaptation to darkness may be useful as an indicator of subclinical autonomic neuropathy in diabetic children.

摘要

使用一种简单的便携式瞳孔计，对63名1型糖尿病儿童和青少年的瞳孔对黑暗的适应性进行了研究。将结果与一组年龄匹配的非糖尿病儿童的结果进行比较，并表示为瞳孔直径与虹膜直径的比值（瞳孔直径百分比）。糖尿病患者的瞳孔直径百分比为61.1±5.8（44.4 - 71.9）%，而对照组为64.2±4.1（53.2 - 72.6）%（p<0.001）。在糖尿病患者中，发现瞳孔对黑暗的异常适应性比其对各种刺激的心率异常变化更为常见。瞳孔对黑暗的适应性可能作为糖尿病儿童亚临床自主神经病变的一个指标。