Jindal Nidhi, Misra Madhukar
Division of Nephrology, Department of Medicine, University of Missouri, Columbia, Missouri, USA.
Hemodial Int. 2014 Oct;18 Suppl 1:S48-51. doi: 10.1111/hdi.12224.
The effect of hemodialysis (HD) on intraocular pressure (IOP) is variable and the exact mechanisms are not clear. Increased, decreased, as well as unchanged IOP has been described during HD in various case reports and studies. Patients with certain types of glaucoma and aqueous outflow obstruction of any other cause might be more susceptible to increase in IOP. This can cause severe eye pain, blurry vision, and headaches, causing significant morbidity for such dialysis patients. Certain changes in dialysis prescription may help relieve the above symptoms. There is a lack of awareness among nephrologists about the effects of HD on IOP. This may be especially relevant in the African American patients who besides having a higher risk of developing end-stage renal disease also have a higher risk of developing glaucoma. Recognition as well as management of signs and symptoms of elevated IOP in the dialysis population is significant morbidity and unnecessary work-up.
血液透析（HD）对眼压（IOP）的影响是多变的，确切机制尚不清楚。在各种病例报告和研究中，均有血液透析期间眼压升高、降低以及无变化的描述。患有某些类型青光眼或任何其他原因导致房水流出受阻的患者可能更容易出现眼压升高。这可能会导致严重的眼痛、视力模糊和头痛，给此类透析患者带来显著的发病率。透析处方的某些改变可能有助于缓解上述症状。肾病学家对血液透析对眼压的影响缺乏认识。这在非裔美国患者中可能尤为相关，他们除了患终末期肾病的风险较高外，患青光眼的风险也较高。认识并处理透析人群中眼压升高的体征和症状，可显著降低发病率并避免不必要的检查。
