牙龈鳞状细胞癌诊断前近期拔牙的临床意义：一种新分类

Clinical implications of recent exodontia before diagnosis of gingival squamous cell carcinoma: A new classification.

作者信息

Cheng Chi-Sheng, Chang Chien-Ming, Hsiao Ying-Lyung, Chan Man-Yee, Lee Chun-Yin, Lee Li-Tzu, Wong Yong-Kie

机构信息

Department of Stomatology, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China.

Department of Oral and Maxillofacial Surgery, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China.

出版信息

Head Neck. 2016 Mar;38(3):339-46. doi: 10.1002/hed.23896. Epub 2015 Jun 16.

DOI:10.1002/hed.23896

PMID:25331819

Abstract

BACKGROUND

The purpose of this study was to clarify the clinical implications of cases with recent dental extractions to establish a new classification of gingival squamous cell carcinoma (SCC).

METHODS

A total of 156 patients were enrolled in this study. The subjects were divided into 3 groups: type I (dentate; n = 46), type II (edentulous; n = 55), and type III (dental extraction; n = 55). Continuous clinical and treatment variables were analyzed by 1-way analysis of variance (ANOVA) or t test, and categorical variables were evaluated by chi-square tests. Assessment of 5-year survival rates were carried out by the Kaplan-Meier analysis, and the influence of related factors was evaluated by the log-rank test.

RESULT

The 55 type III patients showed a high probability of bony invasion (80%) and a lower 5-year survival rate (48%) than the other 2 groups.

CONCLUSION

Our proposed classification may help clinicians to identify patients with gingival SCC who present with more advanced disease status.

摘要

背景

本研究的目的是阐明近期拔牙病例的临床意义，以建立牙龈鳞状细胞癌（SCC）的新分类。

方法

本研究共纳入156例患者。受试者分为3组：I型（有牙列；n = 46）、II型（无牙列；n = 55）和III型（拔牙；n = 55）。连续的临床和治疗变量通过单因素方差分析（ANOVA）或t检验进行分析，分类变量通过卡方检验进行评估。采用Kaplan-Meier分析评估5年生存率，并通过对数秩检验评估相关因素的影响。