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前驱NK细胞淋巴母细胞白血病/淋巴瘤——1例病例报告并文献复习

Precursor NK cell lymphoblastic leukemia/lymphoma-report of a case with literature review.

作者信息

Jain Sonal, Kumar Rajiv, Purohit Abhishek, Pati Hara Prasad

机构信息

Department of Hematology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Hematol Blood Transfus. 2014 Sep;30(Suppl 1):283-5. doi: 10.1007/s12288-014-0360-x. Epub 2014 Mar 14.

Abstract

Precursor Natural Killer (NK) cell lymphoblastic leukemia/lymphoma is a rare entity defined clearly by WHO (2008 WHO classification). However, the pathobiology of this subset of neoplasms is not clearly defined. There is wide disparity in the literature regarding the nomenclature and diagnostic criteria used to diagnose and characterize acute leukemias of presumed NK cell origin. In the present article we report a case of Precursor NK cell lymphoblastic leukemia/lymphoma and review the cases reported after 2008 WHO classification came into vogue, as acute leukemias of NK cell origin.

摘要

前体自然杀伤(NK)细胞淋巴母细胞白血病/淋巴瘤是一种罕见的实体,世界卫生组织(2008年世界卫生组织分类)对其有明确的定义。然而,这类肿瘤的病理生物学尚未明确界定。关于用于诊断和表征假定为NK细胞起源的急性白血病的命名法和诊断标准,文献中存在很大差异。在本文中,我们报告了一例前体NK细胞淋巴母细胞白血病/淋巴瘤病例,并回顾了2008年世界卫生组织分类流行后报告的作为NK细胞起源急性白血病的病例。

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本文引用的文献

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Five Chinese pediatric patients with leukemias possibly arising from immature natural killer cells: clinical features and courses.
Pediatr Hematol Oncol. 2011 Apr;28(3):187-93. doi: 10.3109/08880018.2010.535117. Epub 2011 Jan 27.
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Pediatric myeloid/NK cell precursor lymphoma/leukemia expressing T/NK immunophenotype markers.
Int J Hematol. 2010 Apr;91(3):525-9. doi: 10.1007/s12185-010-0504-1. Epub 2010 Feb 10.
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