Double organ transplantation in cardiac amyloidosis.

作者信息

Gkouziouta Aggeliki, Farmakis Dimitrios, Manginas Athanassios, Sfyrakis Petros, Saroglou Georgios, Adamopoulos Stamatis, Iliodromitis Efstathios K

机构信息

aOnassis Cardiac Surgery Center bSecond Department of Cardiology, Attikon University Hospital cFirst Department of Internal Medicine, Laiko Hospital dDepartment of Cardiology, Mediterraneo Hospital, Athens, Greece.

出版信息

J Cardiovasc Med (Hagerstown). 2016 Feb;17(2):126-9. doi: 10.2459/JCM.0000000000000216.

DOI:10.2459/JCM.0000000000000216

PMID:25333376

Abstract

BACKGROUND

Cardiac amyloidosis, particularly primary or AL amyloidosis, is the most common infiltrative cardiomyopathy and is associated with a poor prognosis. The outcome of cardiac transplantation is generally poor, and almost half of patients die while waiting for the procedure to be done.

PATIENT

We report here the remarkable case of a 63-year-old man with heart failure caused by AL amyloidosis. After a long course, which included rapid deterioration of preexisting heart failure, cardiac arrest, cardiogenic shock, biventricular assist device support, heart transplantation, renal failure, kidney transplantation and finally a life-threatening H1N1 virus pneumonia, the patient managed not only to survive but also to return fully to his previous demanding duties and lifestyle.

DISCUSSION

Early use of left ventricular or biventricular mechanical circulatory support may be beneficial as a bridge to transplantation in patients with cardiac AL amyloidosis.

摘要