Shimoyama Rai, Ban Takushiro, Miyake Katsunori, Isogai Naoko, Ikegaya Yuki, Kawachi Jun, Ogino Hidemitsu, Watanabe Kazunao
Dept. of Surgery, Shonankamakura General Hospital.
Gan To Kagaku Ryoho. 2014 Oct;41(10):1251-3.
A 63-year-old woman with colon cancer who was treated with capecitabine as adjuvant chemotherapy presented with vertigo on day 5, and dysarthria and dysphagia on day 7 of the treatment. Diffusion-weighted magnetic resonance imaging of the brain revealed high signal intensity in the corpus callosum and corona radiata. The patient was diagnosed with acute leukoencephalopathy, and the capecitabine treatment was discontinued. Her symptoms recovered immediately. On the basis of these findings, it can be concluded that diffusion-weighted imaging is useful for the early detection and diagnosis of acute leukoencephalopathy.
一名63岁的结肠癌女性患者接受卡培他滨辅助化疗，在治疗第5天出现眩晕，第7天出现构音障碍和吞咽困难。脑部弥散加权磁共振成像显示胼胝体和放射冠高信号强度。该患者被诊断为急性白质脑病，卡培他滨治疗中断。她的症状立即恢复。基于这些发现，可以得出结论，弥散加权成像对急性白质脑病的早期检测和诊断有用。
