Labbé S, Copin H, Choiset A, Girard S, Barbet J P
Laboratoire d'Histologie Embryologie Cytogénétique, Hôpital Fernand-Widal, Paris.
J Gynecol Obstet Biol Reprod (Paris). 1989;18(8):989-96.
In 30 cases of trisomies 13, 18 and 21, the placenta showed different lesions of hypotrophy, immaturity, hydrops, trophoblastic recurrences or cysts and mineralisation of the trophoblastic basal lamina. These are non specific lesions and can be observed in a variety of conditions, but their association is striking in most cases of trisomies. Different pathological patterns may thus evoke a trisomy, though that diagnosis can only be ascertained by chromosome analysis.
在30例13、18和21三体综合征病例中，胎盘呈现出不同的病变，包括萎缩、不成熟、水肿、滋养层复发或囊肿以及滋养层基底层矿化。这些是非特异性病变，可在多种情况下观察到，但在大多数三体综合征病例中，它们的关联很显著。因此，不同的病理模式可能提示三体综合征，不过只有通过染色体分析才能确诊。
