Morini A, Mossa B, Roscetti C, Florio V
Minerva Ginecol. 1989 Nov;41(11):547-50.
The authors compared the therapeutic efficacy of oestrogen-progestogen combinations with pure progestagen in the urgent treatment of adolescent metrorrhagia. Two groups of adolescents were studied whose haemorrhages were attributed exclusively to disfunction. Every medicine was evaluated as to: 1) effectiveness in completely spotting haemorrhage, 2) any persistence of bleeding, 3) side effects. The therapy was given during 2 consecutive menstrual cycles. Results following treatment with oestrogen-progestogen combinations were favourable, even though side effects were more noticeable.
作者比较了雌激素 - 孕激素联合用药与单纯孕激素在青少年功能性子宫出血紧急治疗中的疗效。研究了两组青少年，其出血完全归因于功能失调。对每种药物进行了以下评估：1）完全止血的有效性，2）出血的持续情况，3）副作用。治疗持续两个连续的月经周期。雌激素 - 孕激素联合用药治疗后的结果是有利的，尽管副作用更明显。
