Lehmann Andrzej, Bobowicz Maciej, Lech Paweł, Orłowski Michał, Siczewski Wiaczesław, Pawlak Maciej, Swietlik Dariusz, Witzling Mieczysław, Michalik Maciej
General and Vascular Surgery Department, Ceynowa Hospital, Wejherowo, Poland.
Department of Oncological Surgery, Medical University of Gdansk, Gdansk, Poland.
Wideochir Inne Tech Maloinwazyjne. 2014 Sep;9(3):351-6. doi: 10.5114/wiitm.2014.44257. Epub 2014 Jul 23.
Laparoscopic sleeve gastrectomy (LSG) and laparoscopic adjustable gastric banding (LAGB) are acceptable options for primary bariatric procedures in patients with body mass index (BMI) 35-55 kg/m(2).
The aim of this study is to compare the effects of these two bariatric procedures 6, 12 and 24 months after surgery.
Two hundred and two patients were included 72 LSG and 130 LAGB patients. The average age was 38.8 ±11.9 and 39.4 ±10.4 years in LSG and LAGB groups, with initial BMI of 44.1 kg/m(2) and 45.2 kg/m(2), p = NS.
The mean percentage of excess weight loss (%EWL) at 6 months for LSG vs. LAGB was 36.3% vs. 30.1% (p = 0.01) and at 12 months was 43.8% vs. 34.6% (p = 0.005). The greatest difference in the mean %EWL at 12 months was observed in patients with initial BMI of 40-49.9 kg/m(2) in favor of LSG (47.5% vs. 35.6%; p = 0.01). Two years after surgery there was no advantage of LSG and in the subgroup of patients with BMI 50-55 kg/m(2) there was a trend in favor of LAGB (57.2% vs. 30%; p = 0.07). The multiple regression model of independent variables (age, gender, initial BMI and the presence of comorbidities) proved insignificant in prediction of the best outcome in means of %EWL for either operative modality. None of these factors in the logistic regression model could determine the type of surgery that should be used in particular patients.
During the first 2 years after surgery, the best results were obtained in women with lower BMI undergoing LSG surgery. The LSG provides greater %EWL after a shorter period of time though the difference decreases in time.
对于体重指数(BMI)为35 - 55kg/m²的患者,腹腔镜袖状胃切除术(LSG)和腹腔镜可调节胃束带术(LAGB)是可接受的原发性减肥手术选择。
本研究的目的是比较这两种减肥手术在术后6、12和24个月的效果。
纳入202例患者,其中72例行LSG手术,130例行LAGB手术。LSG组和LAGB组的平均年龄分别为38.8±11.9岁和39.4±10.4岁,初始BMI分别为44.1kg/m²和45.2kg/m²,p值无统计学意义。
LSG组与LAGB组在6个月时的平均超重减轻百分比(%EWL)分别为36.3%和30.1%(p = 0.01),12个月时分别为43.8%和34.6%(p = 0.005)。在初始BMI为40 - 49.9kg/m²的患者中,12个月时观察到LSG组的平均%EWL差异最大(47.5%对35.6%;p = 0.01)。术后两年,LSG并无优势,在BMI为50 - 55kg/m²的亚组中,有倾向于LAGB的趋势(57.2%对30%;p = 0.07)。自变量(年龄、性别、初始BMI和合并症的存在)的多元回归模型在预测两种手术方式以%EWL衡量的最佳结果时无显著意义。逻辑回归模型中的这些因素均无法确定特定患者应采用的手术类型。
在术后的前两年,接受LSG手术的低BMI女性取得了最佳效果。LSG在较短时间内提供了更高的%EWL,尽管差异会随时间减小。