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通过使用模糊逻辑控制和滞后补偿器的脊髓内多电极微刺激恢复瘫痪肢体的运动功能。

Restoring Motor Functions in Paralyzed Limbs through Intraspinal Multielectrode Microstimulation Using Fuzzy Logic Control and Lag Compensator.

作者信息

Roshani Amir, Erfanian Abbas

机构信息

Iran Neural Technology Centre, Department of Biomedical Engineering, Iran University of Science and Technology (IUST), Tehran, Iran.

出版信息

Basic Clin Neurosci. 2013 Summer;4(3):232-43.

PMID:25337352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4202566/
Abstract

In this paper, a control strategy is proposed for control of ankle movement on animals using intraspinal microstimulation (ISMS). The proposed method is based on fuzzy logic control. Fuzzy logic control is a methodology of intelligent control that mimics human decision making process. This type of control method can be very useful for the complex uncertain systems that their mathematical model is unknown. To increase the stability and speed of the system's response and reduce the steady-state error, we combine the FLC with a lead (lag) compensator. The experiments are conducted on five rats. Microelectrodes are implanted into the spinal cord to provide selective stimulation of plantarflexor and dorsiflexor. The results show that motor functions can be restored using ISMS. Despite the complexity of the spinal neuronal networks and simplicity of the proposed control strategy, our results show that the proposed strategy can provide acceptable tracking control with fast convergence.

摘要

本文提出了一种利用脊髓内微刺激(ISMS)控制动物踝关节运动的控制策略。所提出的方法基于模糊逻辑控制。模糊逻辑控制是一种模仿人类决策过程的智能控制方法。这种控制方法对于数学模型未知的复杂不确定系统非常有用。为了提高系统响应的稳定性和速度并减小稳态误差,我们将模糊逻辑控制器(FLC)与超前(滞后)补偿器相结合。在五只大鼠上进行了实验。将微电极植入脊髓以提供对跖屈肌和背屈肌的选择性刺激。结果表明,使用ISMS可以恢复运动功能。尽管脊髓神经网络复杂且所提出的控制策略简单,但我们的结果表明,所提出的策略可以提供具有快速收敛性的可接受的跟踪控制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e27/4202566/1fbdf99b97c8/BCN-4-232-g008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e27/4202566/1fbdf99b97c8/BCN-4-232-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e27/4202566/3e03a445877b/BCN-4-232-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e27/4202566/13e9c3c760ca/BCN-4-232-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e27/4202566/1fbdf99b97c8/BCN-4-232-g008.jpg

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本文引用的文献

1
Adaptive neuro-fuzzy sliding mode control of multi-joint movement using intraspinal microstimulation.基于脊髓内微刺激的多关节运动自适应神经模糊滑模控制
IEEE Trans Neural Syst Rehabil Eng. 2012 Jul;20(4):499-509. doi: 10.1109/TNSRE.2012.2197828. Epub 2012 Jun 11.
2
Walking after incomplete spinal cord injury using an implanted FES system: a case report.使用植入式功能性电刺激系统在不完全性脊髓损伤后行走:一例报告
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Strategies for generating prolonged functional standing using intramuscular stimulation or intraspinal microstimulation.
使用肌肉内刺激或脊髓内微刺激产生长期功能性站立的策略。
IEEE Trans Neural Syst Rehabil Eng. 2007 Jun;15(2):273-85. doi: 10.1109/TNSRE.2007.897030.
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Intraspinal microstimulation preferentially recruits fatigue-resistant muscle fibres and generates gradual force in rat.脊髓内微刺激优先募集抗疲劳肌纤维并在大鼠体内产生逐渐增强的力量。
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Long-term user perceptions of an implanted neuroprosthesis for exercise, standing, and transfers after spinal cord injury.脊髓损伤后用于运动、站立和转移的植入式神经假体的长期用户认知
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Modulation and vectorial summation of the spinalized frog's hindlimb end-point force produced by intraspinal electrical stimulation of the cord.脊髓内电刺激脊髓所产生的去脊髓青蛙后肢端点力的调制与矢量求和。
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Selective activation of muscle groups in the feline hindlimb through electrical microstimulation of the ventral lumbo-sacral spinal cord.通过对腰骶部脊髓腹侧进行电微刺激选择性激活猫后肢的肌肉群。
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Isometric torque about the knee joint generated by microstimulation of the cat L6 spinal cord.通过微刺激猫的L6脊髓所产生的膝关节等长扭矩。
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