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Brain extracellular space: geometry, matrix and physiological importance.

作者信息

Kamali-Zare Padideh, Nicholson Charles

机构信息

Deptartment of Physiology and Neuroscience, New York University, Medical School NY 10016, New York.

出版信息

Basic Clin Neurosci. 2013 Fall;4(4):282-6.

PMID:25337358
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4202579/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/4202579/38d677420ee5/BCN-4-282-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/4202579/adb320c7d705/BCN-4-282-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/4202579/521fe79ef876/BCN-4-282-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/4202579/92df3fa6eab5/BCN-4-282-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/4202579/848965949c51/BCN-4-282-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/4202579/38d677420ee5/BCN-4-282-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/4202579/adb320c7d705/BCN-4-282-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/4202579/521fe79ef876/BCN-4-282-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/4202579/92df3fa6eab5/BCN-4-282-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/4202579/848965949c51/BCN-4-282-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/317c/4202579/38d677420ee5/BCN-4-282-g005.jpg

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本文引用的文献

1
Diffusion of macromolecules in the brain: implications for drug delivery.大分子在脑内的扩散：对药物递送的影响。
Mol Pharm. 2013 May 6;10(5):1492-504. doi: 10.1021/mp300495e. Epub 2013 Jan 31.
2
Brain Extracellular Space as a Diffusion Barrier.作为扩散屏障的脑细胞外间隙
Comput Vis Sci. 2011 Oct 1;14(7):309-325. doi: 10.1007/s00791-012-0185-9.
3
Calcium diffusion enhanced after cleavage of negatively charged components of brain extracellular matrix by chondroitinase ABC.软骨素酶ABC切割脑细胞外基质的带负电荷成分后，钙扩散增强。
J Physiol. 2009 Aug 15;587(Pt 16):4029-49. doi: 10.1113/jphysiol.2009.170092. Epub 2009 Jun 22.
4
Diffusion in brain extracellular space.脑外间隙中的扩散
Physiol Rev. 2008 Oct;88(4):1277-340. doi: 10.1152/physrev.00027.2007.
5
Extracellular matrix of the central nervous system: from neglect to challenge.中枢神经系统的细胞外基质：从被忽视到成为挑战。
Histochem Cell Biol. 2008 Oct;130(4):635-53. doi: 10.1007/s00418-008-0485-9. Epub 2008 Aug 12.
6
In vivo diffusion of lactoferrin in brain extracellular space is regulated by interactions with heparan sulfate.乳铁蛋白在脑外间隙的体内扩散受其与硫酸乙酰肝素相互作用的调节。
Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8416-21. doi: 10.1073/pnas.0711345105. Epub 2008 Jun 9.
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In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space.利用量子点和葡聚糖进行的体内扩散分析可预测脑细胞外间隙的宽度。
Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5567-72. doi: 10.1073/pnas.0509425103. Epub 2006 Mar 27.
8
Cell cavities increase tortuosity in brain extracellular space.细胞腔增加了脑细胞外空间的曲折度。
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