• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Association of Ca×PO4 product with levels of serum C-reactive protein in regular hemodialysis patients.规律血液透析患者中钙磷乘积与血清C反应蛋白水平的关联
J Renal Inj Prev. 2012 Sep 1;1(2):55-9. doi: 10.12861/jrip.2012.20. eCollection 2012.
2
Linkage of elevated CaxPO4 product with inflammation in maintenance hemodialysis patients.维持性血液透析患者中高钙磷乘积与炎症的关联。
Minerva Urol Nefrol. 2006 Dec;58(4):339-45.
3
A high calcium-phosphate product is associated with high C-reactive protein concentrations in hemodialysis patients.高钙磷乘积与血液透析患者的高C反应蛋白浓度相关。
Nephron Clin Pract. 2005;101(4):c161-7. doi: 10.1159/000087391. Epub 2005 Aug 9.
4
1alpha(OH)D3 One-alpha-hydroxy-cholecalciferol--an active vitamin D analog. Clinical studies on prophylaxis and treatment of secondary hyperparathyroidism in uremic patients on chronic dialysis.1α(OH)D3 一α-羟基胆钙化醇——一种活性维生素 D 类似物。关于慢性透析的尿毒症患者继发性甲状旁腺功能亢进症预防和治疗的临床研究。
Dan Med Bull. 2008 Nov;55(4):186-210.
5
Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national study.慢性血液透析患者血清磷及钙磷乘积与死亡风险的关联：一项全国性研究
Am J Kidney Dis. 1998 Apr;31(4):607-17. doi: 10.1053/ajkd.1998.v31.pm9531176.
6
Close association between parathyroid hormone and left ventricular function and structure in end-stage renal failure patients under maintenance hemodialysis.维持性血液透析的终末期肾衰竭患者甲状旁腺激素与左心室功能及结构的密切关联。
Acta Med Austriaca. 2004 Aug;31(3):67-72.
7
[Changes in mineral metabolism in stage 3, 4, and 5 chronic kidney disease (not on dialysis)].3、4、5期慢性肾脏病（未透析）患者矿物质代谢的变化
Nefrologia. 2008;28 Suppl 3:67-78.
8
Close association between parathyroid hormone and left ventricular function and structure in end-stage renal failure patients under maintenance hemodialysis.维持性血液透析的终末期肾衰竭患者甲状旁腺激素与左心室功能和结构的密切关联。
J Ayub Med Coll Abbottabad. 2004 Apr-Jun;16(2):3-8.
9
RenaGel efficacy in severe secondary hyperparathyroidism.RenaGel对重度继发性甲状旁腺功能亢进的疗效。
Nefrologia. 2002;22(5):448-55.
10
Serum C-reactive protein (CRP) in association with various nutritional parameters in maintenance hemodialysis patients.维持性血液透析患者血清C反应蛋白（CRP）与各种营养参数的关系
Bratisl Lek Listy. 2005;106(12):390-5.

引用本文的文献

1
Atherosclerosis: process, indicators, risk factors and new hopes.动脉粥样硬化：进程、指标、风险因素与新希望
Int J Prev Med. 2014 Aug;5(8):927-46.

本文引用的文献

1
A high calcium-phosphate product is associated with high C-reactive protein concentrations in hemodialysis patients.高钙磷乘积与血液透析患者的高C反应蛋白浓度相关。
Nephron Clin Pract. 2005;101(4):c161-7. doi: 10.1159/000087391. Epub 2005 Aug 9.
2
Mineral metabolism, mortality, and morbidity in maintenance hemodialysis.维持性血液透析中的矿物质代谢、死亡率和发病率
J Am Soc Nephrol. 2004 Aug;15(8):2208-18. doi: 10.1097/01.ASN.0000133041.27682.A2.
3
Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality.终末期肾病中的动脉中层钙化：对全因死亡率和心血管死亡率的影响。
Nephrol Dial Transplant. 2003 Sep;18(9):1731-40. doi: 10.1093/ndt/gfg414.
4
Higher impact of mineral metabolism on cardiovascular mortality in a European hemodialysis population.
Kidney Int Suppl. 2003 Jun(85):S111-4. doi: 10.1046/j.1523-1755.63.s85.26.x.
5
Uremia induces the osteoblast differentiation factor Cbfa1 in human blood vessels.尿毒症可诱导人血管中的成骨细胞分化因子Cbfa1。
Kidney Int. 2003 Mar;63(3):1003-11. doi: 10.1046/j.1523-1755.2003.00820.x.
6
Mortality risk in hemodialysis patients and changes in nutritional indicators: DOPPS.血液透析患者的死亡风险与营养指标变化：透析预后与实践模式研究（DOPPS）
Kidney Int. 2002 Dec;62(6):2238-45. doi: 10.1046/j.1523-1755.2002.00658.x.
7
Inflammation, malnutrition, and cardiac disease as predictors of mortality in hemodialysis patients.炎症、营养不良和心脏病作为血液透析患者死亡率的预测因素。
J Am Soc Nephrol. 2002 Jan;13 Suppl 1:S28-36.
8
Oxidative stress and inflammation in hemodialysis patients.血液透析患者的氧化应激与炎症
Am J Kidney Dis. 2001 Dec;38(6):1408-13. doi: 10.1053/ajkd.2001.29280.
9
Arterial calcifications, arterial stiffness, and cardiovascular risk in end-stage renal disease.终末期肾病中的动脉钙化、动脉僵硬度与心血管风险
Hypertension. 2001 Oct;38(4):938-42. doi: 10.1161/hy1001.096358.
10
Association of elevated serum PO(4), Ca x PO(4) product, and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients.慢性血液透析患者血清磷升高、钙磷乘积及甲状旁腺激素与心脏死亡风险的关联
J Am Soc Nephrol. 2001 Oct;12(10):2131-2138. doi: 10.1681/ASN.V12102131.

规律血液透析患者中钙磷乘积与血清C反应蛋白水平的关联

Association of Ca×PO4 product with levels of serum C-reactive protein in regular hemodialysis patients.

作者信息

Nasri Hamid

机构信息

Department of Nephrology, Shahrekord University of Medical Sciences, Shahrekord, Iran.

出版信息

J Renal Inj Prev. 2012 Sep 1;1(2):55-9. doi: 10.12861/jrip.2012.20. eCollection 2012.

DOI:10.12861/jrip.2012.20
PMID:25340109
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4205986/
Abstract

INTRODUCTION

Numerous studies have attempted to identify risk factors for mortality and morbidity in maintenance hemodialysis patients. In this study we sought to examine the association of the levels of serum C-reactive protein (CRP) with value of Ca×PO4 product, in stable hemodialysis patients.

PATIENTS AND METHODS

Based on the severity of secondary hyperparathyroidism, patients being treated with oral active vitamin D3, calcium carbonate/Renagel tablets at various doses. Fasting serum 25-hydroxy vitamin D and intact serum parathormone and also serum blood urea nitrogen, CRP, calcium, phosphorus, alkaline phosphatase was measured.

RESULTS

A total of 41 patients, enrolled to the study. The mean patients' age were 46(17.6) years. The value of serum CRP of patients was 8.6 (6.6) mg/l (median 6 mg/l). The value of Ca×PO4 product was 50.5(15.5) mg2/dl2 (median: 50 mg(2)/dl(2)). In this study, a significant inverse association between Ca×PO4 product and the age of the patients was seen. A significant positive correlation of logarithm of serum CRP with Ca×PO4 product was found.

CONCLUSION

The result of this study, revealed the need to further attention to hyperphosphatemia in hemodialysis patients.

摘要

引言

众多研究试图确定维持性血液透析患者死亡率和发病率的危险因素。在本研究中，我们旨在探讨稳定血液透析患者血清C反应蛋白（CRP）水平与钙磷乘积值之间的关联。

患者与方法

根据继发性甲状旁腺功能亢进的严重程度，患者接受不同剂量的口服活性维生素D3、碳酸钙/司维拉姆片治疗。检测空腹血清25-羟维生素D、完整血清甲状旁腺激素以及血清血尿素氮、CRP、钙、磷、碱性磷酸酶。

结果

共有41例患者纳入本研究。患者的平均年龄为46（17.6）岁。患者血清CRP值为8.6（6.6）mg/l（中位数6mg/l）。钙磷乘积值为50.5（15.5）mg²/dl²（中位数：50mg²/dl²）。在本研究中，观察到钙磷乘积与患者年龄之间存在显著的负相关。发现血清CRP对数与钙磷乘积之间存在显著正相关。

结论

本研究结果表明，需要进一步关注血液透析患者的高磷血症。