Majeed Abdul, Farooq Imran, Grobler Sias R, Moola M H
Department of Restorative Dental Sciences.
Acta Odontol Scand. 2015 Jul;73(5):387-90. doi: 10.3109/00016357.2014.971865. Epub 2014 Oct 24.
The aim of this in vitro study was to analyze the real hydrogen peroxide (HP) concentration in various commercially available tooth-whitening products containing HP and/or carbamide peroxide (CP).
Sixteen commercially available tooth-whitening products containing various concentrations of CP or HP were investigated. The products were divided into four groups: dentist-supervised home bleaching products (Group 1, n = 5), in-office bleaching products (Group 2, n = 4), over-the-counter bleaching products (Group 3, n = 3) and whitening toothpastes and rinses (Group 4, n = 4). The peroxide concentration was determined using the oxy-reduction titration method. All the reagents used in the study were of analytic grade and freshly prepared before the experiment.
The HP concentration in various dentist-supervised home bleaching products and in-office bleaching products ranged from 3.02-37.08% (expected range = 3-38%). The HP concentration of over-the-counter whitening products ranged from 1.24-5.57% (expected range cannot be estimated as no concentration of active ingredient was provided). Among whitening toothpastes and rinses, Colgate Plax whitening rinse showed more than 1% HP concentration, whereas it was lower than 0.05% in other whitening toothpastes and oral rinses (expected range cannot be estimated as no active ingredient was mentioned).
HP concentration of most of the professional tooth-whitening products was different from the expected concentrations, although the deviations were small and most of the products were close to the expected concentration. No concentration of active ingredient was provided for over-the-counter whitening products and no active ingredient was mentioned for whitening toothpastes and rinses.
本体外研究旨在分析各种市售含过氧化氢（HP）和/或过氧化脲（CP）的牙齿美白产品中实际的过氧化氢浓度。
研究了16种市售含不同浓度CP或HP的牙齿美白产品。这些产品分为四组：牙医指导的家庭美白产品（第1组，n = 5）、诊室美白产品（第2组，n = 4）、非处方美白产品（第3组，n = 3）以及美白牙膏和漱口水（第4组，n = 4）。采用氧化还原滴定法测定过氧化物浓度。研究中使用的所有试剂均为分析纯级，并在实验前新鲜配制。
各种牙医指导的家庭美白产品和诊室美白产品中的HP浓度范围为3.02 - 37.08%（预期范围 = 3 - 38%）。非处方美白产品的HP浓度范围为1.24 - 5.57%（由于未提供活性成分浓度，无法估计预期范围）。在美白牙膏和漱口中，高露洁全效美白漱口水的HP浓度超过1%，而其他美白牙膏和口腔漱口水的HP浓度低于0.05%（由于未提及活性成分，无法估计预期范围）。
大多数专业牙齿美白产品的HP浓度与预期浓度不同，尽管偏差较小且大多数产品接近预期浓度。非处方美白产品未提供活性成分浓度，美白牙膏和漱口水未提及活性成分。
