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[乙肝中度流行地区HBsAg携带者中丁型病毒抗体的检出率]

[Detection rate of antibodies against delta virus among HBsAg carriers in a region with moderate prevalence of hepatitis B].

作者信息

Zhavoronok S V

出版信息

Vopr Virusol. 1989 Nov-Dec;34(6):675-9.

PMID:2534451
Abstract

Radioimmunoassay and enzyme-immunoassay were used to study the detection rates of HBsAg and anti-Delta in blood donors and subjects at high risk of infection with hepatitis B (HB) in the Byelorussian SSR. The republic was found to belong to the region with a moderate prevalence of HB and low prevalence of delta-virus infection. The detection rate of anti-delta antibodies in individual population groups depends on the level of HBsAg carrier state and is closely associated with prolonged treatment in medical institutions. Patients with tuberculosis, rheumatoid arthritis, diabetes mellitus, and cirrhosis of the liver are important reservoirs of HB and delta-virus infection for a region with moderate prevalence of HB virus and low prevalence of delta-virus. Infection with delta-virus is very important in unfavourable outcomes of acute and chronic viral hepatitides in the region.

摘要

采用放射免疫分析法和酶免疫分析法,对白俄罗斯苏维埃社会主义共和国的献血者以及乙型肝炎(HB)高感染风险人群的血液中HBsAg和抗 - δ的检出率进行了研究。结果发现,该共和国属于HB中度流行、δ病毒感染率较低的地区。各人群组中抗 - δ抗体的检出率取决于HBsAg携带状态水平,且与医疗机构的长期治疗密切相关。对于HB病毒中度流行、δ病毒感染率较低的地区,结核病、类风湿性关节炎、糖尿病和肝硬化患者是HB和δ病毒感染的重要储存宿主。在该地区,δ病毒感染对急慢性病毒性肝炎的不良预后非常重要。

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